Sigma-1 receptor ligands improves ventricular repolarization-related ion remodeling in rats with major depression disorder.

Guo, Yan; Zhang, Cui; Chen, Xiuhuan; Liu, Xin; Ye, Tianxin; Fo, Yuhong; Shi, Shaobo; Qu, Chuan; Liang, Jinjun; Shen, Bo; Yang, Bo

Guo, Yan; Zhang, Cui; Chen, Xiuhuan; Liu, Xin; Ye, Tianxin; Fo, Yuhong; Shi, Shaobo; Qu, Chuan; Liang, Jinjun; Shen, Bo; Yang, Bo.

Afiliación

Guo Y; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China.
Zhang C; Cardiovascular Research Institute, Wuhan University, Wuhan, People's Republic of China.
Chen X; Hubei Key Laboratory of Cardiology, Wuhan, People's Republic of China.
Liu X; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China.
Ye T; Cardiovascular Research Institute, Wuhan University, Wuhan, People's Republic of China.
Fo Y; Hubei Key Laboratory of Cardiology, Wuhan, People's Republic of China.
Shi S; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China.
Qu C; Cardiovascular Research Institute, Wuhan University, Wuhan, People's Republic of China.
Liang J; Hubei Key Laboratory of Cardiology, Wuhan, People's Republic of China.
Shen B; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, People's Republic of China.
Yang B; Cardiovascular Research Institute, Wuhan University, Wuhan, People's Republic of China.

Psychopharmacology (Berl) ; 238(2): 487-499, 2021 Feb.

Article en En | MEDLINE | ID: mdl-33140216

Asunto(s)

Canales de Calcio/metabolismo; Trastorno Depresivo Mayor/metabolismo; Ventrículos Cardíacos/metabolismo; Canales de Potasio/metabolismo; Receptores sigma/agonistas; Potenciales de Acción/efectos de los fármacos; Animales; Antidepresivos de Segunda Generación/farmacología; Arritmias Cardíacas/metabolismo; Conducta Animal/efectos de los fármacos; Modelos Animales de Enfermedad; Fluvoxamina/farmacología; Ventrículos Cardíacos/citología; Ventrículos Cardíacos/efectos de los fármacos; Ligandos; Masculino; Miocardio/metabolismo; Técnicas de Placa-Clamp; Ratas; Receptor Sigma-1

Palabras clave

Ionic remodeling; Major depressive disorder; Sigma-1 receptor; Ventricular arrhythmia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Canales de Calcio / Canales de Potasio / Receptores sigma / Trastorno Depresivo Mayor / Ventrículos Cardíacos Límite: Animals Idioma: En Revista: Psychopharmacology (Berl) Año: 2021 Tipo del documento: Article Pais de publicación: Alemania

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