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Two new 7,20-epoxy-ent-kaurane diterpenoids from the aerial parts of Isodon serra.
Hu, Juan-Juan; Li, Bai-Lin; Xie, Jin-Dan; Liang, Hui-Jun; Li, Qian-Ran; Yuan, Jie; Wu, Jie-Wei.
Afiliación
  • Hu JJ; Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
  • Li BL; Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
  • Xie JD; Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
  • Liang HJ; Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
  • Li QR; Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
  • Yuan J; Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
  • Wu JW; Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, P. R. China.
Nat Prod Res ; 36(8): 2021-2027, 2022 Apr.
Article en En | MEDLINE | ID: mdl-33131334
Two new compounds (1 and 2), belonging to C-20 oxygenated ent-kauranes-type diterpenoids, were identified from the aerial parts of Isodon serra. Their structures were elucidated by extensive analysis of HRESI-MS and NMR spectroscopic data. Both these two compounds possess a common 7,20-epoxy-ent-kauranes skeleton with a hydroxyl group rarely occurring at C-13. Compounds 1 and 2 were evaluated for their cytotoxic activity against Hela-60 and HepG2 as well as the antibacterial activity against Staphylococcus aureus, Bacillus cereus and Escherichia coli.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Isodon / Diterpenos de Tipo Kaurano / Diterpenos / Antineoplásicos Fitogénicos Límite: Humans Idioma: En Revista: Nat Prod Res Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Isodon / Diterpenos de Tipo Kaurano / Diterpenos / Antineoplásicos Fitogénicos Límite: Humans Idioma: En Revista: Nat Prod Res Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido