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The Use of Visceral Proteins as Nutrition Markers: An ASPEN Position Paper.
Evans, David C; Corkins, Mark R; Malone, Ainsley; Miller, Sarah; Mogensen, Kris M; Guenter, Peggi; Jensen, Gordon L.
Afiliación
  • Evans DC; System Nutrition Support Team, OhioHealth Trauma and Surgical Services, Columbus, Ohio, USA.
  • Corkins MR; Division of Pediatric Gastroenterology, Le Bonheur Children's Hospital, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
  • Malone A; Nutrition Services, Mount Carmel East Hospital, Columbus, Ohio, USA.
  • Miller S; American Society for Parenteral and Enteral Nutrition, Silver Spring, Maryland, USA.
  • Mogensen KM; Providence Saint Patrick Hospital, University of Montana Skaggs School of Pharmacy, Missoula, Montana, USA.
  • Guenter P; Department of Nutrition, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Jensen GL; Clinical Practice, Quality, and Advocacy, American Society for Parenteral and Enteral Nutrition, Silver Spring, Maryland, USA.
Nutr Clin Pract ; 36(1): 22-28, 2021 Feb.
Article en En | MEDLINE | ID: mdl-33125793
Serum albumin and prealbumin, well-known visceral proteins, have traditionally been considered useful biochemical laboratory values in a nutrition assessment. However, recent literature disputes this contention. The aim of this document is to clarify that these proteins characterize inflammation rather than describe nutrition status or protein-energy malnutrition. Both critical illness and chronic illness are characterized by inflammation and, as such, hepatic reprioritization of protein synthesis occurs, resulting in lower serum concentrations of albumin and prealbumin. In addition, the redistribution of serum proteins occurs because of an increase in capillary permeability. There is an association between inflammation and malnutrition, however, not between malnutrition and visceral-protein levels. These proteins correlate well with patients' risk for adverse outcomes rather than with protein-energy malnutrition. Therefore, serum albumin and prealbumin should not serve as proxy measures of total body protein or total muscle mass and should not be used as nutrition markers. This paper has been approved by the American Society for Parenteral and Enteral Nutrition Board of Directors.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estado Nutricional Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Nutr Clin Pract Asunto de la revista: CIENCIAS DA NUTRICAO / ENFERMAGEM Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estado Nutricional Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Nutr Clin Pract Asunto de la revista: CIENCIAS DA NUTRICAO / ENFERMAGEM Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos