Down-Regulation of microRNA-30d Alleviates Intervertebral Disc Degeneration Through the Promotion of FOXO3 and Suppression of CXCL10.

Xia, Peng; Gao, Xu; Li, Fang; Shao, Liwei; Sun, Yifu

Xia, Peng; Gao, Xu; Li, Fang; Shao, Liwei; Sun, Yifu.

Afiliación

Xia P; Department of Orthopedics, Second Hospital of Jilin University, Changchun, 132000, People's Republic of China.
Gao X; Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin Province, People's Republic of China.
Li F; Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin Province, People's Republic of China.
Shao L; Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin Province, People's Republic of China.
Sun Y; Department of Orthopedics, Second Hospital of Jilin University, Changchun, 132000, People's Republic of China. yifu@jlu.edu.cn.

Calcif Tissue Int ; 108(2): 252-264, 2021 02.

Article en En | MEDLINE | ID: mdl-33118080

Asunto(s)

Quimiocina CXCL10/genética; Proteína Forkhead Box O3/genética; Degeneración del Disco Intervertebral; Animales; Apoptosis; Células Cultivadas; Regulación hacia Abajo; Humanos; Ratones; MicroARNs/genética; Núcleo Pulposo/citología

Palabras clave

C-X-C motif chemokine 10; Forkhead box O3; Intervertebral disc degeneration; MicroRNA-30d; Proliferation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quimiocina CXCL10 / Degeneración del Disco Intervertebral / Proteína Forkhead Box O3 Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Calcif Tissue Int Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos

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