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Clinical manifestations and factors associated with mortality from COVID-19 in older adults: Retrospective population-based study with 9807 older Brazilian COVID-19 patients.
de Souza, Carlos Df; de Arruda Magalhães, Amanda J; Lima, Ayara Jpd; Nunes, Danielle N; de Fátima Machado Soares, Érika; de Castro Silva, Louryanne; Santos, Lucas G; Dos Santos Cardoso, Vitória I; Nobre, Yasmin Vs; do Carmo, Rodrigo F.
Afiliación
  • de Souza CD; Department of Medicine, Post-graduation Program in Health Family, Federal University of Alagoas (UFAL), Arapiraca, Brazil.
  • de Arruda Magalhães AJ; Department of Medicine, Federal University of Alagoas (UFAL), Arapiraca, Brazil.
  • Lima AJ; Department of Medicine, Federal University of Alagoas (UFAL), Arapiraca, Brazil.
  • Nunes DN; Department of Medicine, Federal University of Alagoas (UFAL), Arapiraca, Brazil.
  • de Fátima Machado Soares É; Department of Medicine, Federal University of Alagoas (UFAL), Arapiraca, Brazil.
  • de Castro Silva L; Department of Medicine, Federal University of Alagoas (UFAL), Arapiraca, Brazil.
  • Santos LG; Department of Medicine, Federal University of Alagoas (UFAL), Arapiraca, Brazil.
  • Dos Santos Cardoso VI; Department of Medicine, Federal University of Alagoas (UFAL), Arapiraca, Brazil.
  • Nobre YV; Department of Medicine, Federal University of Alagoas (UFAL), Arapiraca, Brazil.
  • do Carmo RF; Postgraduate Program in Health and Biological Sciences, Federal University of Vale do São Francisco (UNIVASF), Petrolina, Brazil.
Geriatr Gerontol Int ; 20(12): 1177-1181, 2020 Dec.
Article en En | MEDLINE | ID: mdl-33111433
AIM: Older adults are the main risk group for coronavirus disease 2019 (COVID-19). This study aimed to describe the clinical manifestations and factors associated with mortality from COVID-19 among older adults in Brazil. METHODS: A cross-sectional observational study was carried out with data from 9807 cases of COVID-19 among older adults in the state of Alagoas, Brazil. We determined the case fatality rate between age groups and clinical factors associated with mortality. RESULTS: A total of 52.5% (n = 5145) were women, and with an average age of 70.21 ± 8.37 years. The fatality rate was 11.9%, with a higher rate in men (14.4%) compared with women (9.8%). The fatality rate increased with age. The most common manifestations were fever (n = 4926; 50.2%), cough (n = 5737; 58.5%), headache (n = 1980; 20.2%) and fatigue (n = 2022; 20.6%). The most prevalent comorbidities were diabetes (n = 1528; 5.6%), cardiovascular disease (n = 1528; 15.6%) and systemic arterial hypertension (n = 597; 6.1%). The factors associated with mortality were male sex (OR 1.54), age ≥75 years (OR 2.40), dyspnea (OR 2.92), diabetes (OR 2.33), hypertension (OR 1.53) and chronic kidney disease (OR 2.02). CONCLUSIONS: The profile and the risk factors evidenced show the need to adopt mechanisms to protect the elderly population.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: America do sul / Brasil Idioma: En Revista: Geriatr Gerontol Int Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: America do sul / Brasil Idioma: En Revista: Geriatr Gerontol Int Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Japón