Your browser doesn't support javascript.
loading
Does Cue Focality Modulate Age-related Performance in Prospective Memory? An fMRI Investigation.
Scalici, Francesco; Carlesimo, Giovanni Augusto; Santangelo, Valerio; Barban, Francesco; Macaluso, Emiliano; Caltagirone, Carlo; Costa, Alberto.
Afiliación
  • Scalici F; Laboratory of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation , Rome, Italy.
  • Carlesimo GA; Neuroimaging Laboratory, IRCCS Santa Lucia Foundation , Rome, Italy.
  • Santangelo V; Laboratory of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation , Rome, Italy.
  • Barban F; Department of Systems Medicine, Tor Vergata University , Rome, Italy.
  • Macaluso E; Neuroimaging Laboratory, IRCCS Santa Lucia Foundation , Rome, Italy.
  • Caltagirone C; Department of Philosophy, Social Sciences & Education, University of Perugia , Perugia, Italy.
  • Costa A; Laboratory of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation , Rome, Italy.
Exp Aging Res ; 47(1): 1-20, 2021.
Article en En | MEDLINE | ID: mdl-33107393
How prospective memory (PM) weakens with increasing age has been largely debated. We hypothesized that automatic and strategic PM processes, respectively mediated by focal and non-focal cues, are differently affected by aging, even starting from 50-60 years of age. We investigated this issue using a 2 × 2 design in which focal and non-focal experimental conditions were created by varying the conjoint nature of the ongoing task (lexical decision vs. syllable matching tasks) and the PM cue (words vs. syllables). In the whole-brain analysis we found that the left inferior frontal gyrus and the middle cingulate cortex were more activated when young compared to older individuals performed a PM task; moreover, the anterior cingulate cortex was selectively activated during non-focal PM when the cues were words. In a region-of-interest analysis we observed that the medial and the lateral portions of the rostral prefrontal cortex were associated with the focal and non-focal conditions respectively, more in young than in older adults. Our findings provide evidence in support of early age-related differences in automatic/strategic PM functioning.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Señales (Psicología) / Memoria Episódica Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Humans Idioma: En Revista: Exp Aging Res Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Señales (Psicología) / Memoria Episódica Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Humans Idioma: En Revista: Exp Aging Res Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos