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[Progress of epithelial-mesenchymal transition in respiratory system and the modulatory mechanism of cell adhesion].
Tan, Mei-Ling; Long, Chun-Jiao; Jiang, Wang; Wang, Jin-Mei; Pi, Jiao; Qin, Xiao-Qun; Xiang, Yang.
Afiliación
  • Tan ML; Department of Physiology, School of Basic Medical Science, Central South University, Changsha 410078, China.
  • Long CJ; Department of Physiology, School of Basic Medical Science, Central South University, Changsha 410078, China.
  • Jiang W; Department of Physiology, School of Basic Medical Science, Central South University, Changsha 410078, China.
  • Wang JM; Department of Physiology, School of Basic Medical Science, Central South University, Changsha 410078, China.
  • Pi J; Department of Physiology, School of Basic Medical Science, Central South University, Changsha 410078, China.
  • Qin XQ; Department of Physiology, School of Basic Medical Science, Central South University, Changsha 410078, China.
  • Xiang Y; Department of Physiology, School of Basic Medical Science, Central South University, Changsha 410078, China. xiangyang@csu.edu.cn.
Sheng Li Xue Bao ; 72(5): 605-616, 2020 Oct 25.
Article en Zh | MEDLINE | ID: mdl-33106831
Epithelial-mesenchymal transition (EMT) plays an important role in the development and pathogenesis of respiratory system. Epithelial cells are characterized by well-developed, intercellular contacts, whereas EMT triggers the sequential destabilization of cell-cell adhesive junctions. The dynamic remodeling of the epithelial cell adhesion molecules is important for maintaining the integrity and normal function of epithelium. This paper reviews the research progress of EMT in lung development, lung injury repair and chronic lung diseases, and summarizes the effect of cell junctions and cell adhesion molecules on EMT molecular events.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sistema Respiratorio / Transición Epitelial-Mesenquimal Idioma: Zh Revista: Sheng Li Xue Bao Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: China
Buscar en Google
Añadir a Mi BVS
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sistema Respiratorio / Transición Epitelial-Mesenquimal Idioma: Zh Revista: Sheng Li Xue Bao Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: China