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A comparison of the corneal biomechanics in pseudoexfoliation glaucoma, primary open-angle glaucoma and healthy controls using Corvis ST.
Pradhan, Zia Sultan; Deshmukh, Sujit; Dixit, Shivani; Sreenivasaiah, Shruthi; Shroff, Sujani; Devi, Sathi; Webers, Carroll A B; Rao, Harsha Laxmana.
Afiliación
  • Pradhan ZS; Department of glaucoma, Narayana Nethralaya Eye Hospital, Bangalore, Karnataka, India.
  • Deshmukh S; Department of glaucoma, Narayana Nethralaya Eye Hospital, Bangalore, Karnataka, India.
  • Dixit S; Department of glaucoma, Narayana Nethralaya Eye Hospital, Bangalore, Karnataka, India.
  • Sreenivasaiah S; Department of glaucoma, Narayana Nethralaya Eye Hospital, Bangalore, Karnataka, India.
  • Shroff S; Department of glaucoma, Narayana Nethralaya Eye Hospital, Bangalore, Karnataka, India.
  • Devi S; Department of glaucoma, Narayana Nethralaya Eye Hospital, Bangalore, Karnataka, India.
  • Webers CAB; University Eye Clinic Maastricht, University Medical Center, Maastricht, The Netherlands.
  • Rao HL; Department of glaucoma, Narayana Nethralaya Eye Hospital, Bangalore, Karnataka, India.
PLoS One ; 15(10): e0241296, 2020.
Article en En | MEDLINE | ID: mdl-33104764
PURPOSE: To compare the corneal biomechanical parameters between pseudoexfoliation glaucoma (PXG), primary open-angle glaucoma (POAG) and healthy controls using Corvis ST. METHODS: A prospective, cross-sectional study was conducted which included 132 treatment-naïve eyes which underwent Corvis ST. The study cohort comprised of 44 eyes with PXG, 42 eyes with POAG and 46 healthy controls. Corneal biomechanical parameters, which included corneal velocities, length of corneal applanated surface, deformation amplitude (DA), peak distance and radius of curvature, were compared between the groups using analysis of variance models. RESULTS: The 3 groups were demographically similar. The mean IOP was 15.7 ±3 mmHg in the control group, 21.3 ±5 mmHg in the POAG group and 25.8 ±7 mmHg in the PXG group (p<0.0001). Corneal pachymetry was similar across the 3 groups. Mean DA was significantly lower (p<0.0001) in the PXG group (0.86 ±0.18 mm) compared to the POAG group (0.97 ±0.14mm) and the control group (1.10 ±0.15mm). Corneal velocities were also found to be statistically significantly different between the groups. However, after adjusting for IOP, there was no difference in any of the biomechanical parameters between the 3 groups. CONCLUSION: Corneal biomechanical parameters measured on Corvis ST are not different between eyes with PXG, POAG and healthy controls after adjusting for IOP.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tonometría Ocular / Glaucoma de Ángulo Abierto / Síndrome de Exfoliación / Córnea Tipo de estudio: Observational_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tonometría Ocular / Glaucoma de Ángulo Abierto / Síndrome de Exfoliación / Córnea Tipo de estudio: Observational_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos