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PCSK9 rs11591147 R46L loss-of-function variant protects against liver damage in individuals with NAFLD.
Grimaudo, Stefania; Bartesaghi, Stefano; Rametta, Raffaela; Marra, Fabio; Margherita Mancina, Rosellina; Pihlajamäki, Jussi; Kakol-Palm, Dorota; Andréasson, Anne-Christine; Dongiovanni, Paola; Ludovica Fracanzani, Anna; Lori, Giulia; Männistö, Ville; Pellegrini, Giovanni; Bohlooly-Y, Mohammad; Pennisi, Grazia; Maria Pipitone, Rosaria; Spagnuolo, Rocco; Craxì, Antonio; Lindén, Daniel; Valenti, Luca; Romeo, Stefano; Petta, Salvatore.
Afiliación
  • Grimaudo S; Sezione di Gastroenterologia e Epatologia, PROMISE, University of Palermo, Palermo, Italy.
  • Bartesaghi S; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Rametta R; General Medicine and Metabolic Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
  • Marra F; Dipartimento di Medicina Sperimentale e Clinica, University of Florence, Florence, Italy.
  • Margherita Mancina R; Research Center DENOTHE, University of Florence, Florence, Italy.
  • Pihlajamäki J; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Gothenburg, Sweden.
  • Kakol-Palm D; Departments of Medicine and Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
  • Andréasson AC; Clinical Nutrition and Obesity Center, Kuopio University Hospital, Kuopio, Finland.
  • Dongiovanni P; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Ludovica Fracanzani A; Bioscience Cardiovascular, Research and Early Development Cardiovascular, Renal and Metabolism, R&D, AstraZeneca, Gothenburg, Sweden.
  • Lori G; General Medicine and Metabolic Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
  • Männistö V; General Medicine and Metabolic Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
  • Pellegrini G; Departments of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
  • Bohlooly-Y M; Dipartimento di Medicina Sperimentale e Clinica, University of Florence, Florence, Italy.
  • Pennisi G; Research Center DENOTHE, University of Florence, Florence, Italy.
  • Maria Pipitone R; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
  • Spagnuolo R; Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Craxì A; Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Lindén D; Sezione di Gastroenterologia e Epatologia, PROMISE, University of Palermo, Palermo, Italy.
  • Valenti L; Sezione di Gastroenterologia e Epatologia, PROMISE, University of Palermo, Palermo, Italy.
  • Romeo S; Department of Experimental and Clinical Medicine, University Magna Graecia, Catanzaro, Italy.
  • Petta S; Sezione di Gastroenterologia e Epatologia, PROMISE, University of Palermo, Palermo, Italy.
Liver Int ; 41(2): 321-332, 2021 02.
Article en En | MEDLINE | ID: mdl-33091218
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad del Hígado Graso no Alcohólico / Proproteína Convertasa 9 Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Liver Int Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad del Hígado Graso no Alcohólico / Proproteína Convertasa 9 Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Liver Int Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos