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Thrombotic Complications in Venous Malformations: Are There Differences Between Facial and Other Localizations?
Soudet, Simon; Dakpe, Stephanie; Le Gloan, Sandra; Carmi, Esther; Arnault, Jean Philippe; Testelin, Sylvie; Plancq, Marie-Christine; Devauchelle, Bernard; Sevestre, Marie Antoinette.
Afiliación
  • Soudet S; Department of Vascular Medicine, 36673Centre Hospitalo-Universitaired'Amiens Avenue Laennec, Amiens, France.
  • Dakpe S; Maxillo-facial Surgery Department, 36673Centre Hospitalo-Universitaired'Amiens Avenue Laennec, Amiens, France.
  • Le Gloan S; Department of Vascular Medicine, 36673Centre Hospitalo-Universitaired'Amiens Avenue Laennec, Amiens, France.
  • Carmi E; Department of Dermatology, 36673Centre Hospitalo-Universitaired'Amiens Avenue Laennec, Amiens, France.
  • Arnault JP; Department of Dermatology, 36673Centre Hospitalo-Universitaired'Amiens Avenue Laennec, Amiens, France.
  • Testelin S; Maxillo-facial Surgery Department, 36673Centre Hospitalo-Universitaired'Amiens Avenue Laennec, Amiens, France.
  • Plancq MC; Department of Pediatric Surgery, 36673Centre Hospitalo-Universitaired'Amiens Avenue Laennec, Amiens, France.
  • Devauchelle B; Maxillo-facial Surgery Department, 36673Centre Hospitalo-Universitaired'Amiens Avenue Laennec, Amiens, France.
  • Sevestre MA; Department of Vascular Medicine, 36673Centre Hospitalo-Universitaired'Amiens Avenue Laennec, Amiens, France.
Clin Appl Thromb Hemost ; 26: 1076029620968143, 2020.
Article en En | MEDLINE | ID: mdl-33085511
Venous thrombosis (VT) is a frequent complication in venous malformations (VM) in relation with blood stasis and localized intravascular coagulopathy (LIC). Our aim was to describe the clinical characteristics and the treatment of patients with facial and non facial VM with VT. We implemented an observational retrospective study of patients with VM followed between 2002 and 2017. We compared features of facial and non facial VM. Descriptive and bivariate statistics were computed and the P value was set at 0.05. Fifty patients were included between 2002 and 2017. 24 of them were women (44%). The median age of the patients at diagnosis was 16,5 [8-31] years. The median follow up was 2 [2; 4] years. In non facial VM venous thrombosis occurred in 12 cases. In facial VM, 3 patients had thrombotic complication (15%). We demonstrate no difference of VT between facial VM and other localization. No patients had clinical risk factors for VT at diagnosis. Our study showed that VT is a frequent complication of VM and its proportion is not different between facial and non facial VM. Studies are needed to confirm the role of LIC in VT in VM, particularly in facial VM.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malformaciones Vasculares Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Clin Appl Thromb Hemost Asunto de la revista: ANGIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malformaciones Vasculares Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Clin Appl Thromb Hemost Asunto de la revista: ANGIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos