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Physical activity energy expenditure and fat-free mass: relationship with metabolic syndrome in overweight or obese postmenopausal women.
Maréchal, René; Ghachem, Ahmed; Prud'homme, Denis; Rabasa-Lhoret, Rémi; Dionne, Isabelle J; Brochu, Martin.
Afiliación
  • Maréchal R; Research Centre on Aging, CIUSSS de l'Estrie-CHUS, Sherbrooke, QC J1H 4C4, Canada.
  • Ghachem A; Faculty of Physical Activity Sciences, University of Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.
  • Prud'homme D; Research Centre on Aging, CIUSSS de l'Estrie-CHUS, Sherbrooke, QC J1H 4C4, Canada.
  • Rabasa-Lhoret R; School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
  • Dionne IJ; Institut du Savoir Montfort, Ottawa, ON K1K 0T2, Canada.
  • Brochu M; Department of Nutrition, Faculty of Medicine, University of Montreal, Montréal, QC H3T 1A8, Canada.
Appl Physiol Nutr Metab ; 46(4): 389-396, 2021 Apr.
Article en En | MEDLINE | ID: mdl-33080144
Menopause transition is associated with detrimental changes in physical activity, body composition, and metabolic profile. Although physical activity energy expenditure (PAEE) is inversely associated with metabolic syndrome (MetS) in individuals at higher risk of cardiovascular disease, the association is unknown in low-risk individuals. The aim of the study was to investigate the association between PAEE and MetS (prevalence and severity) in inactive overweight or obese postmenopausal women with a low Framingham Risk Score (<10%). Cross-sectional data of 126 participants were divided into quartiles based on PAEE (Quartile (Q)1 = lowest PAEE) while fat-free mass (FFM) and fat mass were measured by dual-energy X-ray absorptiometry. MetS prevalence was significantly different between Q1 and Q4 (37.9% vs 13.3%, p = 0.03). After controlling for potential confounders, MetS severity was negatively associated with PAEE (B = -0.057, p < 0.01) and positively with FFM (B = 0.038, p < 0.001). Moderation analyses indicated that a greater FFM exacerbated the association between PAEE and MetS severity in Q1 and Q2 (PAEE × FFM; B = -0.004; p = 0.1). Our results suggest that displaying a low FRS and lower PAEE increase MetS prevalence and severity. In addition, greater FFM interacts with lower PAEE to worsens MetS severity, while higher PAEE lessened this effect. Novelty: Inactive individuals displaying higher daily PAEE also have a lower MetS prevalence. Greater FFM is associated with a worse MetS severity where a higher PAEE mitigated this deleterious effect in our cohort.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Composición Corporal / Ejercicio Físico / Síndrome Metabólico / Metabolismo Energético / Sobrepeso / Obesidad Tipo de estudio: Etiology_studies / Health_economic_evaluation / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Appl Physiol Nutr Metab Asunto de la revista: CIENCIAS DA NUTRICAO / FISIOLOGIA / MEDICINA ESPORTIVA / METABOLISMO Año: 2021 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Canadá

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Composición Corporal / Ejercicio Físico / Síndrome Metabólico / Metabolismo Energético / Sobrepeso / Obesidad Tipo de estudio: Etiology_studies / Health_economic_evaluation / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Appl Physiol Nutr Metab Asunto de la revista: CIENCIAS DA NUTRICAO / FISIOLOGIA / MEDICINA ESPORTIVA / METABOLISMO Año: 2021 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Canadá