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Peryton: a manual collection of experimentally supported microbe-disease associations.
Skoufos, Giorgos; Kardaras, Filippos S; Alexiou, Athanasios; Kavakiotis, Ioannis; Lambropoulou, Anastasia; Kotsira, Vasiliki; Tastsoglou, Spyros; Hatzigeorgiou, Artemis G.
Afiliación
  • Skoufos G; Department of Electrical & Computer Engineering, Univ. of Thessaly, Volos 38221, Greece.
  • Kardaras FS; Hellenic Pasteur Institute, Athens 11521, Greece.
  • Alexiou A; Hellenic Pasteur Institute, Athens 11521, Greece.
  • Kavakiotis I; DIANA-Lab, Department of Computer Science and Biomedical Informatics, Univ. of Thessaly, Lamia 351 31, Greece.
  • Lambropoulou A; Hellenic Pasteur Institute, Athens 11521, Greece.
  • Kotsira V; DIANA-Lab, Department of Computer Science and Biomedical Informatics, Univ. of Thessaly, Lamia 351 31, Greece.
  • Tastsoglou S; Department of Electrical & Computer Engineering, Univ. of Thessaly, Volos 38221, Greece.
  • Hatzigeorgiou AG; Hellenic Pasteur Institute, Athens 11521, Greece.
Nucleic Acids Res ; 49(D1): D1328-D1333, 2021 01 08.
Article en En | MEDLINE | ID: mdl-33080028
We present Peryton (https://dianalab.e-ce.uth.gr/peryton/), a database of experimentally supported microbe-disease associations. Its first version constitutes a novel resource hosting more than 7900 entries linking 43 diseases with 1396 microorganisms. Peryton's content is exclusively sustained by manual curation of biomedical articles. Diseases and microorganisms are provided in a systematic, standardized manner using reference resources to create database dictionaries. Information about the experimental design, study cohorts and the applied high- or low-throughput techniques is meticulously annotated and catered to users. Several functionalities are provided to enhance user experience and enable ingenious use of Peryton. One or more microorganisms and/or diseases can be queried at the same time. Advanced filtering options and direct text-based filtering of results enable refinement of returned information and the conducting of tailored queries suitable to different research questions. Peryton also provides interactive visualizations to effectively capture different aspects of its content and results can be directly downloaded for local storage and downstream analyses. Peryton will serve as a valuable source, enabling scientists of microbe-related disease fields to form novel hypotheses but, equally importantly, to assist in cross-validation of findings.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Bacterianas / Bases de Datos Factuales / Enfermedades Neurodegenerativas / Interacciones Huésped-Patógeno / Enfermedades Gastrointestinales / Micosis / Neoplasias Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2021 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Bacterianas / Bases de Datos Factuales / Enfermedades Neurodegenerativas / Interacciones Huésped-Patógeno / Enfermedades Gastrointestinales / Micosis / Neoplasias Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2021 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido