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Role of clinical, functional and social factors in the association between multimorbidity and quality of life: Findings from the Survey of Health, Ageing and Retirement in Europe (SHARE).
Makovski, Tatjana T; Le Coroller, Gwenaëlle; Putrik, Polina; Choi, Yun Hee; Zeegers, Maurice P; Stranges, Saverio; Ruiz Castell, Maria; Huiart, Laetitia; van den Akker, Marjan.
Afiliación
  • Makovski TT; Department of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg.
  • Le Coroller G; Department of Family Medicine, Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
  • Putrik P; Chairgroup of Complex Genetics and Epidemiology, Nutrition and Metabolism in Translational Research, Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
  • Choi YH; Competence Centre for Methodology and Statistics, Department of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg.
  • Zeegers MP; Department of Health Services Research, Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
  • Stranges S; Department of Epidemiology & Biostatistics, Western University, London, Ontario, Canada.
  • Ruiz Castell M; Chairgroup of Complex Genetics and Epidemiology, Nutrition and Metabolism in Translational Research, Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
  • Huiart L; Department of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg.
  • van den Akker M; Department of Epidemiology & Biostatistics, Western University, London, Ontario, Canada.
PLoS One ; 15(10): e0240024, 2020.
Article en En | MEDLINE | ID: mdl-33079931
OBJECTIVE: An increasing number of diseases is linked to deterioration of quality of life (QoL). Part of this association can be explained by socio-economic factors, which are most commonly accounted for. Our aim was to explore the potential contribution of other factors related to clinical burden, social interaction and functioning. METHODS: A cross-sectional analysis was conducted on wave 6 of the population-based Survey of Health, Ageing and Retirement in Europe (SHARE), among participants aged 50+ (n = 67 179). The Control, Autonomy, Self-Realization and Pleasure (CASP-12v1) questionnaire measured QoL. The association between number of diseases and QoL was tested in a mixed-effects linear regression model. The base model controlled for socio-economic characteristics. Factors of interest (symptoms, polypharmacy, unmet care needs, utilisation of care, social network, personal and financial help, loneliness and activities of daily living (ADL) with instrumental activities (IADL)) were added to the base model one at a time and tested for relevance (i.e. change in the ß-coefficient of the number of conditions of 15% or more). RESULTS: Symptoms, polypharmacy, loneliness and ADL/IADL appeared relevant and were retained in the final model. The association between number of conditions and QoL in the base model was -2.44 [95% CI: -2.72; -2.16], while this association was -0.76 [95%CI: -0.97; -0.54] after all relevant factors were included. CONCLUSION: Factors beyond the socio-economic circumstances play an important role in explaining the association between number of conditions and QoL. These factors should be considered to better estimate the impact of chronic diseases on QoL, and for improving patient care.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Multimorbilidad Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Equity_inequality / Patient_preference Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Luxemburgo Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Multimorbilidad Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Equity_inequality / Patient_preference Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Luxemburgo Pais de publicación: Estados Unidos