[Genome-wide studies of primary open-angle glaucoma]. / Polnogenomnye issledovaniya pervichnoi otkrytougol'noi glaukomy.
Vestn Oftalmol
; 136(5): 129-135, 2020.
Article
en Ru
| MEDLINE
| ID: mdl-33056974
The article reviews literature on developmental stages of genome-wide association studies (GWAS) of primary open-angle glaucoma (POAG). This problem is currently developing and one of the most complex in ophthalmology. The article considers main GWAS of POAG and established GWAS-significant polymorphisms associated with the disease. The topic of genome-wide studies of primary open-angle glaucoma will be of certain interest to ophthalmologists, materials on GWAS-significant loci can be used both in the selection of polymorphisms in replicative studies of POAG in various populations of Russia, and to expand ideas about the molecular genetic mechanisms of the development of the disease.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Glaucoma de Ángulo Abierto
/
Estudio de Asociación del Genoma Completo
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
País/Región como asunto:
Asia
/
Europa
Idioma:
Ru
Revista:
Vestn Oftalmol
Año:
2020
Tipo del documento:
Article
País de afiliación:
Rusia
Pais de publicación:
Rusia