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Thrombocytopenia Caused by Dexamethasone in a Patient with Colorectal Cancer.
Taguchi, Ryosuke; Tsuchihashi, Kenji; Okumura, Yuta; Nakano, Michitaka; Yoshihiro, Tomoyasu; Ohmura, Hirofumi; Tsuruta, Nobuhiro; Hanamura, Fumiyasu; Yamaguchi, Kyoko; Ito, Mamoru; Ariyama, Hiroshi; Kusaba, Hitoshi; Akashi, Koichi; Baba, Eishi.
Afiliación
  • Taguchi R; Department of Hematology, Oncology and Cardiovascular Medicine, Kyushu University Hospital, Japan.
  • Tsuchihashi K; Department of Hematology, Oncology and Cardiovascular Medicine, Kyushu University Hospital, Japan.
  • Okumura Y; Department of Hematology, Oncology and Cardiovascular Medicine, Kyushu University Hospital, Japan.
  • Nakano M; Department of Hematology, Oncology and Cardiovascular Medicine, Kyushu University Hospital, Japan.
  • Yoshihiro T; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Japan.
  • Ohmura H; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Japan.
  • Tsuruta N; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Japan.
  • Hanamura F; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Japan.
  • Yamaguchi K; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Japan.
  • Ito M; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Japan.
  • Ariyama H; Department of Hematology, Oncology and Cardiovascular Medicine, Kyushu University Hospital, Japan.
  • Kusaba H; Department of Hematology, Oncology and Cardiovascular Medicine, Kyushu University Hospital, Japan.
  • Akashi K; Department of Medicine and Biosystemic Science, Graduate School of Medical Sciences, Kyushu University, Japan.
  • Baba E; Department of Oncology and Social Medicine, Graduate School of Medical Sciences, Kyushu University, Japan.
Intern Med ; 59(20): 2571-2575, 2020.
Article en En | MEDLINE | ID: mdl-33055471
Drug-induced immune thrombocytopenia (DITP) is an important cause of thrombocytopenia. A 73-year-old man with relapsed rectal carcinoma received S-1, oxaliplatin and bevacizumab combination therapy (SOX+Bev). Dexamethasone was administered as an antiemetic prophylaxis. On day 2 of the first cycle, thrombocytopenia (8,000/µL) was observed. We sequentially omitted any drugs suspected to possibly induce thrombocytopenia and confirmed dexamethasone as the cause of thrombocytopenia. DITP induced by synthetic corticosteroids is very rare and this is the first case report of DITP induced by dexamethasone. Although rare, DITP due to synthetic corticosteroids including dexamethasone should be a differential diagnosis among patients receiving synthetic corticosteroids with thrombocytopenia.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trombocitopenia / Dexametasona / Antieméticos Tipo de estudio: Diagnostic_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trombocitopenia / Dexametasona / Antieméticos Tipo de estudio: Diagnostic_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón