Your browser doesn't support javascript.
loading
The role of multiparametric resonance and biopsy in prostate cancer detection: comparison with definitive histological report after laparoscopic/robotic radical prostatectomy.
Rapisarda, S; Bada, M; Crocetto, F; Barone, B; Arcaniolo, D; Polara, A; Imbimbo, C; Grosso, G.
Afiliación
  • Rapisarda S; Department of Urology, Ospedale Pederzoli, Peschiera del Garda, Verona, Italy.
  • Bada M; Department of Urology, San Bassiano Hospital, Bassano del Grappa, Vicenza, Italy.
  • Crocetto F; Department of Neurosciences, Reproductive and Odontostomatological Sciences, School of Medicine, Federico II University of Naples, Via Sergio Pansini, no 5, 80131, Naples, Italy. felice.crocetto@unina.it.
  • Barone B; Department of Neurosciences, Reproductive and Odontostomatological Sciences, School of Medicine, Federico II University of Naples, Via Sergio Pansini, no 5, 80131, Naples, Italy.
  • Arcaniolo D; Department of Woman, Child and General and Specialized Surgery, Urology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
  • Polara A; Department of Urology, Ospedale Pederzoli, Peschiera del Garda, Verona, Italy.
  • Imbimbo C; Department of Neurosciences, Reproductive and Odontostomatological Sciences, School of Medicine, Federico II University of Naples, Via Sergio Pansini, no 5, 80131, Naples, Italy.
  • Grosso G; Department of Urology, Ospedale Pederzoli, Peschiera del Garda, Verona, Italy.
Abdom Radiol (NY) ; 45(12): 4178-4184, 2020 12.
Article en En | MEDLINE | ID: mdl-33048224
PURPOSE: Magnetic Resonance Imaging (MRI) targeted biopsy increases overall detection rates and decreases the risk of clinically insignificant PCa detection. The aim of this retrospective study is to compare concordance rates regarding side of lesion and Gleason Score at fusion targeted/systematic biopsy and MRI with the definitive histologic report of prostatectomy specimen. METHODS: 115 patients underwent multiparametric (mp) MRI and successively fusion targeted/systematic biopsy. 107 patients, with a positive biopsy for PCa, further underwent laparoscopic/robotic radical prostatectomy. We compared surgical histologic report with biopsy histologic report for side of lesion and Gleason Score. We further compared PIRADS score at mpMRI with Gleason Score of both histologic reports. RESULTS: Concordance rate for mpMRI lesion side was 74% compared to biopsy and 52.3% compared to surgical histologic report (p < 0.0001). Fusion targeted/systematic biopsy reported a concordance rate with surgical histologic report of 67.3% for side of the lesion, while Gleason Score was concordant for 73.6% for clinically significant cancer (Gleason Score ≥ 7) (p < 0.0001). PIRADS score ≥ 3 was further associated with clinically significant cancer at surgical histologic report in 92.4% of cases (p = 0.359). CONCLUSION: Multiparametric MRI of the prostate reaches a good and improvable accuracy in the detection of suspicious PCa before biopsy. A combined approach of fusion targeted and systematic biopsy could further increase the overall accuracy in PCa diagnosis, especially in biopsy-naïve patients, reaching concordance rates with definitive histologic report up to 52.3% and 85.5%.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Laparoscopía / Procedimientos Quirúrgicos Robotizados Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Humans / Male Idioma: En Revista: Abdom Radiol (NY) Año: 2020 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Laparoscopía / Procedimientos Quirúrgicos Robotizados Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Humans / Male Idioma: En Revista: Abdom Radiol (NY) Año: 2020 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos