Enhanced O-succinyl-l-homoserine production by recombinant Escherichia coli &#916;IJBB*TrcmetL/pTrc-metA<sup>fbr</sup> -Trc-thrA<sup>fbr</sup> -yjeH via multilevel fermentation optimization.

Zhu, W-Y; Niu, K; Liu, P; Fan, Y-H; Liu, Z-Q; Zheng, Y-G

Enhanced O-succinyl-l-homoserine production by recombinant Escherichia coli ΔIJBB*TrcmetL/pTrc-metA^fbr -Trc-thrA^fbr -yjeH via multilevel fermentation optimization.

Zhu, W-Y; Niu, K; Liu, P; Fan, Y-H; Liu, Z-Q; Zheng, Y-G.

Afiliación

Zhu WY; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, P.R.China.
Niu K; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, P.R.China.
Liu P; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, P.R.China.
Fan YH; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, P.R.China.
Liu ZQ; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, P.R.China.
Zheng YG; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, P.R.China.

J Appl Microbiol ; 130(6): 1960-1971, 2021 Jun.

Article en En | MEDLINE | ID: mdl-33025634

Asunto(s)

Escherichia coli/genética; Escherichia coli/metabolismo; Homoserina/análogos & derivados; Redes y Vías Metabólicas/genética; Técnicas de Cultivo Celular por Lotes; Medios de Cultivo/química; Medios de Cultivo/metabolismo; Fermentación; Glucosa/análisis; Glucosa/metabolismo; Homoserina/análisis; Homoserina/metabolismo; Ingeniería Metabólica; Treonina/análisis; Treonina/metabolismo

Palabras clave

O-succinyl-l-homoserine; fed-batch strategy; fermentation optimization

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Escherichia coli / Redes y Vías Metabólicas / Homoserina Idioma: En Revista: J Appl Microbiol Asunto de la revista: MICROBIOLOGIA Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido

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