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Mechanoactivation of NOX2-generated ROS elicits persistent TRPM8 Ca2+ signals that are inhibited by oncogenic KRas.
Pratt, Stephen J P; Lee, Rachel M; Chang, Katarina T; Hernández-Ochoa, Erick O; Annis, David A; Ory, Eleanor C; Thompson, Keyata N; Bailey, Patrick C; Mathias, Trevor J; Ju, Julia A; Vitolo, Michele I; Schneider, Martin F; Stains, Joseph P; Ward, Christopher W; Martin, Stuart S.
Afiliación
  • Pratt SJP; Program in Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, MD 21201; sjppratt@umaryland.edu ssmartin@som.umaryland.edu.
  • Lee RM; Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Chang KT; Department of Physiology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Hernández-Ochoa EO; Marlene and Stewart Greenebaum National Cancer Institute Comprehensive Cancer Center, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Annis DA; Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Ory EC; Department of Physiology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Thompson KN; Marlene and Stewart Greenebaum National Cancer Institute Comprehensive Cancer Center, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Bailey PC; Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Mathias TJ; Department of Physiology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Ju JA; Marlene and Stewart Greenebaum National Cancer Institute Comprehensive Cancer Center, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Vitolo MI; Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Schneider MF; Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Stains JP; Marlene and Stewart Greenebaum National Cancer Institute Comprehensive Cancer Center, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Ward CW; Department of Pharmacology, School of Medicine, University of Maryland, Baltimore, MD 21201.
  • Martin SS; Department of Physiology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Proc Natl Acad Sci U S A ; 117(42): 26008-26019, 2020 10 20.
Article en En | MEDLINE | ID: mdl-33020304

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mama / Calcio / Proteínas Proto-Oncogénicas p21(ras) / Especies Reactivas de Oxígeno / Mecanotransducción Celular / Canales Catiónicos TRPM / NADPH Oxidasa 2 Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mama / Calcio / Proteínas Proto-Oncogénicas p21(ras) / Especies Reactivas de Oxígeno / Mecanotransducción Celular / Canales Catiónicos TRPM / NADPH Oxidasa 2 Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos