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Consensus mutagenesis approach improves the thermal stability of system xc - transporter, xCT, and enables cryo-EM analyses.
Oda, Kazumasa; Lee, Yongchan; Wiriyasermkul, Pattama; Tanaka, Yoko; Takemoto, Mizuki; Yamashita, Keitaro; Nagamori, Shushi; Nishizawa, Tomohiro; Nureki, Osamu.
Afiliación
  • Oda K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
  • Lee Y; Department of Structural Biology, Max Planck Institute of Biophysics, Frankfurt, Germany.
  • Wiriyasermkul P; Department of Collaborative Research for Bio-Molecular Dynamics, Nara Medical University, Nara, Japan.
  • Tanaka Y; Department of Collaborative Research for Bio-Molecular Dynamics, Nara Medical University, Nara, Japan.
  • Takemoto M; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
  • Yamashita K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
  • Nagamori S; Department of Collaborative Research for Bio-Molecular Dynamics, Nara Medical University, Nara, Japan.
  • Nishizawa T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
  • Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Protein Sci ; 29(12): 2398-2407, 2020 12.
Article en En | MEDLINE | ID: mdl-33016372
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microscopía por Crioelectrón / Sistema de Transporte de Aminoácidos y/ Límite: Animals / Humans Idioma: En Revista: Protein Sci Asunto de la revista: BIOQUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microscopía por Crioelectrón / Sistema de Transporte de Aminoácidos y/ Límite: Animals / Humans Idioma: En Revista: Protein Sci Asunto de la revista: BIOQUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos