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Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2.
Peng, Tao; Liu, Xiangpei; Adams, L Garry; Agarwal, Girish; Akey, Bruce; Cirillo, Jeffrey; Deckert, Volker; Delfan, Sahar; Fry, Edward; Han, Zehua; Hemmer, Philip; Kattawar, George; Kim, Moochan; Lee, Ming-Che; Lu, Chaoyang; Mogford, Jon; Nessler, Reed; Neuman, Ben; Nie, Xiaoyu; Pan, Jianwei; Pryor, Jane; Rajil, Navid; Shih, Yanhua; Sokolov, Alexei; Svidzinsky, Anatoly; Wang, Dawei; Yi, Zhenhuan; Zheltikov, Aleksei; Scully, Marlan.
Afiliación
  • Peng T; Texas A&M University, College Station, Texas 77843, USA.
  • Adams LG; Texas A&M University, College Station, Texas 77843, USA.
  • Agarwal G; Texas A&M University, College Station, Texas 77843, USA.
  • Akey B; Texas A&M University, College Station, Texas 77843, USA.
  • Cirillo J; Texas A&M University, College Station, Texas 77843, USA.
  • Delfan S; Texas A&M University, College Station, Texas 77843, USA.
  • Fry E; Texas A&M University, College Station, Texas 77843, USA.
  • Han Z; Texas A&M University, College Station, Texas 77843, USA.
  • Hemmer P; Texas A&M University, College Station, Texas 77843, USA.
  • Kattawar G; Texas A&M University, College Station, Texas 77843, USA.
  • Kim M; Texas A&M University, College Station, Texas 77843, USA.
  • Lee MC; Texas A&M University, College Station, Texas 77843, USA.
  • Lu C; University of Science and Technology of China, Hefei 230026, China.
  • Mogford J; Texas A&M University, College Station, Texas 77843, USA.
  • Nessler R; Texas A&M University, College Station, Texas 77843, USA.
  • Neuman B; Texas A&M University, College Station, Texas 77843, USA.
  • Pan J; University of Science and Technology of China, Hefei 230026, China.
  • Pryor J; Texas A&M University, College Station, Texas 77843, USA.
  • Rajil N; Texas A&M University, College Station, Texas 77843, USA.
  • Shih Y; University of Maryland, Baltimore County, Baltimore, Maryland 21250, USA.
  • Sokolov A; Texas A&M University, College Station, Texas 77843, USA.
  • Svidzinsky A; Texas A&M University, College Station, Texas 77843, USA.
  • Wang D; Zhejiang University, Hangzhou 310027, China.
  • Yi Z; Texas A&M University, College Station, Texas 77843, USA.
Appl Phys Lett ; 117(12): 120601, 2020 Sep 21.
Article en En | MEDLINE | ID: mdl-33012808
Lateral flow assay (LFA) has long been used as a biomarker detection technique. It has advantages such as low cost, rapid readout, portability, and ease of use. However, its qualitative readout process and lack of sensitivity are limiting factors. We report a photon-counting approach to accurately quantify LFAs while enhancing sensitivity. In particular, we demonstrate that the density of SARS-CoV-2 antibodies can be quantified and measured with an enhanced sensitivity using this simple laser optical analysis.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Qualitative_research Idioma: En Revista: Appl Phys Lett Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Qualitative_research Idioma: En Revista: Appl Phys Lett Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos