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A Siderophore Analog of Fimsbactin from Acinetobacter Hinders Growth of the Phytopathogen Pseudomonas syringae and Induces Systemic Priming of Immunity in Arabidopsis thaliana.
Betoudji, Fabrice; Abd El Rahman, Taha; Miller, Marvin J; Ghosh, Manuka; Jacques, Mario; Bouarab, Kamal; Malouin, François.
Afiliación
  • Betoudji F; Département de Biologie, Faculté des Sciences, Université de Sherbrooke, QC J1K 2R1, Canada.
  • Abd El Rahman T; Département de Biologie, Faculté des Sciences, Université de Sherbrooke, QC J1K 2R1, Canada.
  • Miller MJ; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
  • Ghosh M; Rosetree Corporate Center, Hsiri Therapeutics, Inc., Media, PA 19063, USA.
  • Jacques M; Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC J2S 2M2, Canada.
  • Bouarab K; Département de Biologie, Faculté des Sciences, Université de Sherbrooke, QC J1K 2R1, Canada.
  • Malouin F; Département de Biologie, Faculté des Sciences, Université de Sherbrooke, QC J1K 2R1, Canada.
Pathogens ; 9(10)2020 Sep 30.
Article en En | MEDLINE | ID: mdl-33007866
Siderophores produced in soil by plant growth-promoting rhizobacteria (PGPRs) play several roles, including nutrient mobilizers and can be useful as plants defense elicitors. We investigated the role of a synthetic mixed ligand bis-catechol-mono-hydroxamate siderophore (SID) that mimics the chemical structure of a natural siderophore, fimsbactin, produced by Acinetobacter spp. in the resistance against the phytopathogen Pseudomonas syringaepv tomato DC3000 (Pst DC3000), in Arabidopsis thaliana. We first tested the antibacterial activity of SID against Pst DC3000 in vitro. After confirming that SID had antibacterial activity against Pst DC3000, we tested whether the observed in vitro activity could translate into resistance of Arabidopsis to Pst DC3000, using bacterial loads as endpoints in a plant infection model. Furthermore, using quantitative polymerase chain reaction, we explored the molecular actors involved in the resistance of Arabidopsis induced by SID. Finally, to assure that SID would not interfere with PGPRs, we tested in vitro the influence of SID on the growth of a reference PGPR, Bacillus subtilis. We report here that SID is an antibacterial agent as well as an inducer of systemic priming of resistance in A. thaliana against Pst DC3000, and that SID can, at the same time, promote growth of a PGPR.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pathogens Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pathogens Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Suiza