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Clinical Epidemiology of Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) in Japan: Report of the COVID-19 Registry Japan.
Matsunaga, Nobuaki; Hayakawa, Kayoko; Terada, Mari; Ohtsu, Hiroshi; Asai, Yusuke; Tsuzuki, Shinya; Suzuki, Setsuko; Toyoda, Ako; Suzuki, Kumiko; Endo, Mio; Fujii, Naoki; Suzuki, Michiyo; Saito, Sho; Uemura, Yukari; Shibata, Taro; Kondo, Masashi; Izumi, Kazuo; Terada-Hirashima, Junko; Mikami, Ayako; Sugiura, Wataru; Ohmagari, Norio.
Afiliación
  • Matsunaga N; AMR Clinical Reference Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Hayakawa K; AMR Clinical Reference Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Terada M; Department of Infectious Diseases, Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Ohtsu H; Department of Infectious Diseases, Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Asai Y; Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
  • Tsuzuki S; Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
  • Suzuki S; AMR Clinical Reference Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Toyoda A; AMR Clinical Reference Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Suzuki K; Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
  • Endo M; Department of Infectious Diseases, Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Fujii N; Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
  • Suzuki M; AMR Clinical Reference Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Saito S; AMR Clinical Reference Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Uemura Y; AMR Clinical Reference Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Shibata T; Department of Infectious Diseases, Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Kondo M; Department of Infectious Diseases, Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
  • Izumi K; Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
  • Terada-Hirashima J; Biostatistics Division, Center for Research Administration and Support, National Cancer Center, Tokyo, Japan.
  • Mikami A; Center for Clinical Trial and Research Support, Fujita Health University, Aichi, Japan.
  • Sugiura W; Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
  • Ohmagari N; Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
Clin Infect Dis ; 73(11): e3677-e3689, 2021 12 06.
Article en En | MEDLINE | ID: mdl-32986793
BACKGROUND: There is limited understanding of the characteristics of patients with coronavirus disease 2019 (COVID-19) requiring hospitalization in Japan. METHODS: This study included 2638 cases enrolled from 227 healthcare facilities that participated in the COVID-19 Registry Japan (COVIREGI-JP). The inclusion criteria for enrollment of a case in COVIREGI-JP are both (1) a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test and (2) inpatient treatment at a healthcare facility. RESULTS: The median age of hospitalized patients with COVID-19 was 56 years (interquartile range [IQR], 40-71 years). More than half of cases were male (58.9%, 1542/2619). Nearly 60% of the cases had close contact to confirmed or suspected cases of COVID-19. The median duration of symptoms before admission was 7 days (IQR, 4-10 days). The most common comorbidities were hypertension (15%, 396/2638) and diabetes without complications (14.2%, 374/2638). The number of nonsevere cases (68.2%, n = 1798) was twice the number of severe cases (31.8%, n = 840) at admission. The respiratory support during hospitalization includes those who received no oxygen support (61.6%, 1623/2636) followed by those who received supplemental oxygen (29.9%, 788/2636) and invasive mechanical ventilation/extracorporeal membrane oxygenation (8.5%, 225/2636). Overall, 66.9% (1762/2634) of patients were discharged home, while 7.5% (197/2634) died. CONCLUSIONS: We identified the clinical epidemiological features of COVID-19 in hospitalized patients in Japan. When compared with existing inpatient studies in other countries, these results demonstrated fewer comorbidities and a trend towards lower mortality.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Prognostic_studies / Screening_studies Límite: Adult / Aged / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Prognostic_studies / Screening_studies Límite: Adult / Aged / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos