Clinical experience with ethynodiol diacetate 0.5 mg daily as an oral contraceptive.
Contraception
; 35(2): 121-34, 1987 Feb.
Article
en En
| MEDLINE
| ID: mdl-3297483
ABSTRACT
PIP: Femulen, a progestogen only oral contraceptive (ethynodiol diacetate 0.5mg), was evaluated for its contraceptive efficacy and safety in 425 women aged between 16 and 47 years. This was a multicenter open study carried out in General Practice and Family Planning clinics. 5 pregnancies were reported, 3 of which were a result of patient failure. The net pregnancy rate at 1 year for method failure was 0.5%. No ectopic pregnancy was reported. The median length of the menstrual period was between 4 and 5 days and the average length of the non-bleeding interval remained between 24 and 25 days throughout the study. Blood pressure on the whole remained within normal limits. However, there was a small increase in both systolic and diastolic blood pressure which did not reach significant levels. Body weight was unaltered and no abnormality was found in cervical smears. Femulen was shown to be an effective and acceptable contraceptive in women of varying ages.
Palabras clave
Clinical Research; Contraception; Contraception Research; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods; Developed Countries; England; Europe; Evaluation; Family Planning; Female Contraception; Northern Europe; Oral Contraceptives; Research Methodology; Research Report; United Kingdom
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Diacetato de Etinodiol
Tipo de estudio:
Clinical_trials
/
Etiology_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Middle aged
/
Pregnancy
Idioma:
En
Revista:
Contraception
Año:
1987
Tipo del documento:
Article
Pais de publicación:
Estados Unidos