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A placebo-controlled, double-blind, randomized study of recombinant thrombomodulin (ART-123) to prevent oxaliplatin-induced peripheral neuropathy.
Kotaka, Masahito; Saito, Yoji; Kato, Takeshi; Satake, Hironaga; Makiyama, Akitaka; Tsuji, Yasushi; Shinozaki, Katsunori; Fujiwara, Toshiyoshi; Mizushima, Tsunekazu; Harihara, Yasushi; Nagata, Naoki; Kurihara, Naoto; Ando, Masahiko; Kusakawa, Genichi; Sakai, Takumi; Uchida, Yugo; Takamoto, Mikihiro; Kimoto, Saki; Hyodo, Ichinosuke.
Afiliación
  • Kotaka M; Gastrointestinal Cancer Center, Sano Hospital, 2-5-1 Shimizugaoka, Tarumi-ku, Kobe-shi, Hyogo, 655-0031, Japan. tomomakotaka6410@yahoo.co.jp.
  • Saito Y; Department of Anesthesiology, Shimane University Faculty of Medicine, 89-1 Enyacho, Izumo City, Shimane, 693-8501, Japan.
  • Kato T; Department of Gastroenterological Surgery, Kansai Rosai Hospital, 3-1-69 Inabaso, Amagasaki-shi, Hyogo, 660-8511, Japan.
  • Satake H; Colorectal Surgery, National Hospital Organization Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka City, Osaka, 540-0006, Japan.
  • Makiyama A; Department of Medical Oncology, Kobe City Medical Center General Hospital, 2-1-1 Minatojimaminamimachi, Chuo-ku, Kobe-city, Hyogo, 650-0047, Japan.
  • Tsuji Y; Cancer Treatment Center, Kansai Medical University Hospital, 2-3-1 Shin-machi, Hirakata City, Osaka, 573-1191, Japan.
  • Shinozaki K; Department of Hematology/Oncology, Japan Community Healthcare Organization Kyushu Hospital, 1-8-1 Kishinoura, Yahatanishi-ku, Kitakyusyu-shi, Fukuoka, 806-8501, Japan.
  • Fujiwara T; Cancer Center, Gifu University Hospital, 1-1 Yanagido, Gifu, 501-1194, Japan.
  • Mizushima T; Department of Medical Oncology, Tonan Hospital, Kita 4-jo Nishi 7-chome 3-8, Chuo-ku, Sapporo-shi, Hokkaido, 060-0004, Japan.
  • Harihara Y; Division of Clinical Oncology, Hiroshima Prefectural Hospital, 1-5-54 Ujinakanda, Minami-ku, Hiroshima-shi, Hiroshima, 734-8530, Japan.
  • Nagata N; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama-city, Okayama, 700-8558, Japan.
  • Kurihara N; Department of Gastrointestinal Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
  • Ando M; Department of Surgery, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, Shinagawa-ku, Tokyo, 141-8625, Japan.
  • Kusakawa G; Department of Surgery, Kitakyushu General Hospital, 1-1 Higashijono-machi, Kokurakita-ku, Kitakyushu, 802-8517, Japan.
  • Sakai T; Department of Surgery, Nerima General Hospital, 1-24-1 Asahigaoka, Nerima-ku, Tokyo, 176-8530, Japan.
  • Uchida Y; Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8560, Japan.
  • Takamoto M; Clinical Development Center, Asahi Kasei Pharma Corporation, 1-1-2 Yurakucho, Chiyoda-ku, Tokyo, 100-0006, Japan.
  • Kimoto S; Clinical Development Center, Asahi Kasei Pharma Corporation, 1-1-2 Yurakucho, Chiyoda-ku, Tokyo, 100-0006, Japan.
  • Hyodo I; Clinical Development Center, Asahi Kasei Pharma Corporation, 1-1-2 Yurakucho, Chiyoda-ku, Tokyo, 100-0006, Japan.
Cancer Chemother Pharmacol ; 86(5): 607-618, 2020 11.
Article en En | MEDLINE | ID: mdl-32965539
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Trombomodulina / Neoplasias del Colon / Enfermedades del Sistema Nervioso Periférico / Oxaliplatino Tipo de estudio: Clinical_trials / Diagnostic_studies / Incidence_studies / Prognostic_studies Aspecto: Patient_preference Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Chemother Pharmacol Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Alemania
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Trombomodulina / Neoplasias del Colon / Enfermedades del Sistema Nervioso Periférico / Oxaliplatino Tipo de estudio: Clinical_trials / Diagnostic_studies / Incidence_studies / Prognostic_studies Aspecto: Patient_preference Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Chemother Pharmacol Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Alemania