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Physical Function Measured Prior to Lung Transplantation Is Associated With Posttransplant Patient Outcomes.
Mayer, Kirby P; Henning, Angela N; Gaines, Kathryn M; Cassity, Evan P; Morris, Peter E; Villasante Tezanos, Alejandro G; Johnson, Carrie A; Lee, James T; Baz, Maher; Dupont-Versteegden, Esther E.
Afiliación
  • Mayer KP; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky. Electronic address: Kirby.mayer@uky.edu.
  • Henning AN; Inpatient Rehabilitation Department, Chandler Medical Center, University of Kentucky, Lexington, Kentucky.
  • Gaines KM; Inpatient Rehabilitation Department, Chandler Medical Center, University of Kentucky, Lexington, Kentucky.
  • Cassity EP; Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kentucky, Lexington, Kentucky.
  • Morris PE; Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kentucky, Lexington, Kentucky.
  • Villasante Tezanos AG; Department of Statistics, College of Arts and Sciences, University of Kentucky, Lexington, Kentucky.
  • Johnson CA; Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kentucky, Lexington, Kentucky.
  • Lee JT; Department of Radiology, University of Kentucky, Lexington, Kentucky.
  • Baz M; Cardiovascular and Thoracic Surgery, Lung Transplant, University of Kentucky, Lexington, Kentucky.
  • Dupont-Versteegden EE; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky.
Transplant Proc ; 53(1): 288-295, 2021.
Article en En | MEDLINE | ID: mdl-32950260
INTRODUCTION: The primary objective of this study was to determine whether pretransplant physical function is correlated with posttransplantation outcomes. METHODS: We performed a retrospective study of patients that participated in pretransplantation screening and subsequently underwent lung transplantation. Pretransplant variables of interest included demographics, muscle mass, body composition, physical function, and physical frailty. Correlation tests were performed to assess relationships with significance set at 0.05. RESULTS: Twenty-five patients with a mean age of 57 ± 13 years (68% male) with pretransplant lung allocation score of 45 ± 14 were included. This cohort had a 3-year mortality rate of 32% (n = 8). Pretransplant 4-m gait speed was significantly related to performance on the Short Physical Performance Battery (r = 0.74, P = .02) and distance ambulated on the 6-minute walk test (r = 0.62, P = .07) at hospital discharge. Older age was associated with slower gait speed and worse performance on sit-to-stand testing at hospital discharge (r = -0.76, P = .01 and r = -0.75, P = .01, respectively). Statistically, only diagnosis of cystic fibrosis was associated with 3-year mortality. DISCUSSION: Our study demonstrates that demographic, clinical, and physical function assessed prior to lung transplantation may be indicators of functional recovery.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aptitud Física / Trasplante de Pulmón / Resultado del Tratamiento Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Transplant Proc Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aptitud Física / Trasplante de Pulmón / Resultado del Tratamiento Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Transplant Proc Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos