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Impact of attitudes and beliefs on antiretroviral treatment adherence intention among HIV-positive pregnant and breastfeeding women in Zambia.
Nutor, Jerry John; Slaughter-Acey, Jaime C; Marquez, Shannon P; DiMaria-Ghalili, Rose Ann; Momplaisir, Florence; Oladimeji, Kelechi Elizabeth; Jemmott, Loretta S.
Afiliación
  • Nutor JJ; Family Health Care Nursing Department, School of Nursing, University of California, 2 Koret Way, Suite N431G, San Francisco, CA, 94143-0608, USA. jerry.nutor@ucsf.edu.
  • Slaughter-Acey JC; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, 55454, USA.
  • Marquez SP; Undergraduate Global Engagement, Columbia University, New York City, NY, 110027, USA.
  • DiMaria-Ghalili RA; College of Nursing and Health Professions, Drexel University, Philadelphia, PA, 19104, USA.
  • Momplaisir F; Department of Medicine, Hospital of University of the Pennsylvania, Philadelphia, PA, 19102, USA.
  • Oladimeji KE; Department of Public Health, Faculty of Health Sciences, University of Fort Hare, Alice, Eastern Cape, South Africa.
  • Jemmott LS; College of Nursing and Health Professions, Drexel University, Philadelphia, PA, 19104, USA.
BMC Public Health ; 20(1): 1410, 2020 Sep 16.
Article en En | MEDLINE | ID: mdl-32938415
OBJECTIVE: The aim of this study was to investigate if attitudes or behavioral beliefs about antiretroviral therapy (ART) influence ART adherence intention among pregnant and breastfeeding women in Zambia. METHODS: We recruited 150 HIV-positive women receiving ART in urban (Lusaka) and rural (Sinazongwe) districts of Zambia. Generalized modified Poisson regression models were used to assess the extent to which adherence intention was influenced by attitude toward ART or behavioral beliefs about ART. RESULTS: Intention to adhere to ART differed significantly by income, knowledge about HIV transmission, attitudes, and behavioral beliefs (all Ps < .05). In addition, strong intention to adhere to ART differed by urban (69%) and rural (31%) place of residence (P ≤ .01). In adjusted models, women in the weak adherence intention group were more likely to be older, have less knowledge about HIV transmission, and have a more negative attitude toward ART (PR 0.74; 95% CI 0.67-0.82). Behavioral belief about ART, however, was significant in unadjusted model (PR 0.85; 95% CI 0.76-0.94) but not significant after adjusting for covariates such as age, knowledge of transmission, and district locality. CONCLUSION: Compared to behavioral beliefs, attitudes about ART were more influential for intention to adhere. This knowledge will help inform effective and appropriate ART counseling for pregnant and breastfeeding women at different points along their ART time course.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Fármacos Anti-VIH Límite: Female / Humans / Pregnancy País/Región como asunto: Africa Idioma: En Revista: BMC Public Health Asunto de la revista: SAUDE PUBLICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Fármacos Anti-VIH Límite: Female / Humans / Pregnancy País/Región como asunto: Africa Idioma: En Revista: BMC Public Health Asunto de la revista: SAUDE PUBLICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido