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Empowering patients living with diabetes mellitus to cease smoking will improve lower limb perfusion.
Camilleri, Terence; Camilleri, Liberato; Midolo, Yvonne; Papanas, Nikolaos; Gatt, Alfred; Formosa, Cynthia.
Afiliación
  • Camilleri T; Podiatry Department, Faculty of Health Sciences, University of Malta, Msida, Malta.
  • Camilleri L; Department of Statistics and Operations Research, Faculty of Science, University of Malta, Msida, Malta.
  • Midolo Y; Podiatry Department, Faculty of Health Sciences, University of Malta, Msida, Malta.
  • Papanas N; Diabetes Centre-Diabetic Foot Clinic, Second Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
  • Gatt A; Podiatry Department, Faculty of Health Sciences, University of Malta, Msida, Malta.
  • Formosa C; Podiatry Department, Faculty of Health Sciences, University of Malta, Msida, Malta.
J Addict Dis ; 39(1): 74-80, 2021.
Article en En | MEDLINE | ID: mdl-32935653
Background: To evaluate the effect of smoking on arterial perfusion and to determine whether smoking cessation would result in a significant improvement on the circulation of persons living with type 2 diabetes mellitus (T2DM).Methods: A nonexperimental comparative quantitative research was conducted amongst 32 participants with type 2 diabetes mellitus (T2DM) and controlled hyperlipidemia [smokers (n = 11), past smokers (n = 11), and nonsmokers (n = 10); aged ≥ 40 & ≤ 85 years]. Participants were matched for age, body mass index, estimated glomerular filtration rate, packet years, duration of diabetes mellitus, and glycated hemoglobin levels (HbA1c, %) utilizing frequency distribution matching. Peripheral arterial disease (PAD) was assessed utilizing the toe brachial pressure index (TBPI). TBPI value of ≤0.7 was suggestive of PAD while >0.7 was considered normal.Results: Sixty-four limbs were included for analyses. One-way ANOVA showed significant difference in the TBPI scores between the three categories (p < 0.05), with the current smokers demonstrating the lowest TBPI means (0.544), followed by past smokers (0.649) and nonsmokers having the highest TBPI (0.781). Tukey's post-hoc analysis confirmed significant difference in TBPI between current and nonsmokers (p = 0.024). Linear regression of risk predictors identified packet years as the best predictor (p = 0.004), followed by HbA1c (0.019).Conclusions: Results suggest that smoking has a significant effect on PAD in T2DM and that improved perfusion is found in past smokers. Empowering patients to cease smoking will result in better limb perfusion.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Perfusión / Poder Psicológico / Cese del Hábito de Fumar / Extremidad Inferior / Diabetes Mellitus Tipo 2 / Enfermedad Arterial Periférica Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: J Addict Dis Asunto de la revista: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Año: 2021 Tipo del documento: Article País de afiliación: Malta Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Perfusión / Poder Psicológico / Cese del Hábito de Fumar / Extremidad Inferior / Diabetes Mellitus Tipo 2 / Enfermedad Arterial Periférica Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male Idioma: En Revista: J Addict Dis Asunto de la revista: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Año: 2021 Tipo del documento: Article País de afiliación: Malta Pais de publicación: Reino Unido