Your browser doesn't support javascript.
loading
Anastomotic Stricture Definition After Esophageal Atresia Repair: Role of Endoscopic Stricture Index.
Parente, Giovanni; Gargano, Tommaso; Ruggeri, Giovanni; Maffi, Michela; D'Antonio, Simone; Sacchet, Elisa; Lima, Mario.
Afiliación
  • Parente G; Department of Pediatric Surgery, Sant'Orsola-Malpighi University Hospital, Bologna, Italy. Electronic address: giovanni.parente@outlook.com.
  • Gargano T; Department of Pediatric Surgery, Sant'Orsola-Malpighi University Hospital, Bologna, Italy.
  • Ruggeri G; Department of Pediatric Surgery, Sant'Orsola-Malpighi University Hospital, Bologna, Italy.
  • Maffi M; Department of Pediatric Surgery, Sant'Orsola-Malpighi University Hospital, Bologna, Italy.
  • D'Antonio S; Department of Pediatric Surgery, Sant'Orsola-Malpighi University Hospital, Bologna, Italy.
  • Sacchet E; Department of Pediatric Surgery, Sant'Orsola-Malpighi University Hospital, Bologna, Italy.
  • Lima M; Department of Pediatric Surgery, Sant'Orsola-Malpighi University Hospital, Bologna, Italy.
J Surg Res ; 257: 572-578, 2021 01.
Article en En | MEDLINE | ID: mdl-32927323
BACKGROUND: To evaluate the feasibility and efficacy of endoscopic stricture index (SIEN) to define anastomotic strictures (ASs) and to predict the need of dilatations. MATERIALS AND METHODS: A retrospective longitudinal study was conducted on patients who underwent esophageal atresia repair from 1998-2020 (ethical committee approval CHPED-05-20-AS). SIEN was calculated on the first endoscopy performed as follows: (D - d)/D, where D is the maximum diameter of lumen of the upper esophagus close to the AS and d is the diameter of lumen of the stricture. Nonparametric variables were examined using Wilcoxon-Mann-Whitney test, and continuous variables were analyzed using Spearman's test and regression analysis. A P value <0.05 was considered statistically significant. The sensitivity, specificity, and positive and negative predictive values of SIEN were also calculated, and a receiver operating characteristic curve was designed. RESULTS: A total of 46 patients were included in the study. A statistically significant correlation was found between SIEN and number of dilations (Spearman's correlation rate, 0.7; P < 0.0005). A SIEN threshold value ≥0.6 showed sensitivity of 100%, specificity of 80%, positive predictive value of 54%, negative predictive value of 100%, and the area under the curve of 84%. CONCLUSIONS: SIEN seems to be a good AS definer and prognostic tool; our study suggests that an AS could be defined by a SIEN ≥0.6.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Índice de Severidad de la Enfermedad / Atresia Esofágica / Estenosis Esofágica Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Ethics Límite: Female / Humans / Male / Newborn Idioma: En Revista: J Surg Res Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Índice de Severidad de la Enfermedad / Atresia Esofágica / Estenosis Esofágica Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Ethics Límite: Female / Humans / Male / Newborn Idioma: En Revista: J Surg Res Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos