Generation of highly activated, antigen-specific tumor-infiltrating CD8<sup>+</sup> T cells induced by a novel T cell-targeted immunotherapy.

Vila-Leahey, Ava; MacKay, Alecia; Portales-Cervantes, Liliana; Weir, Genevieve M; Merkx-Jacques, Alexandra; Stanford, Marianne M

Generation of highly activated, antigen-specific tumor-infiltrating CD8⁺ T cells induced by a novel T cell-targeted immunotherapy.

Vila-Leahey, Ava; MacKay, Alecia; Portales-Cervantes, Liliana; Weir, Genevieve M; Merkx-Jacques, Alexandra; Stanford, Marianne M.

Afiliación

Vila-Leahey A; Research and Development, IMV Inc, Dartmouth, NS, Canada.
MacKay A; Research and Development, IMV Inc, Dartmouth, NS, Canada.
Portales-Cervantes L; Research and Development, IMV Inc, Dartmouth, NS, Canada.
Weir GM; Research and Development, IMV Inc, Dartmouth, NS, Canada.
Merkx-Jacques A; Research and Development, IMV Inc, Dartmouth, NS, Canada.
Stanford MM; Research and Development, IMV Inc, Dartmouth, NS, Canada.

Oncoimmunology ; 9(1): 1782574, 2020 06 27.

Article en En | MEDLINE | ID: mdl-32923145

Asunto(s)

Neoplasias; Receptor de Muerte Celular Programada 1; Animales; Linfocitos T CD8-positivos; Femenino; Inmunoterapia; Linfocitos Infiltrantes de Tumor; Ratones; Ratones Endogámicos C57BL

Palabras clave

CD8+ T cells; Combination immunotherapy; T cell activation; checkpoint inhibitors; flow cytometry; immunology

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptor de Muerte Celular Programada 1 / Neoplasias Límite: Animals Idioma: En Revista: Oncoimmunology Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos

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