The Sd<sup>a</sup> Synthase B4GALNT2 Reduces Malignancy and Stemness in Colon Cancer Cell Lines Independently of Sialyl Lewis X Inhibition.

Pucci, Michela; Gomes Ferreira, Inês; Malagolini, Nadia; Ferracin, Manuela; Dall'Olio, Fabio

The Sd^a Synthase B4GALNT2 Reduces Malignancy and Stemness in Colon Cancer Cell Lines Independently of Sialyl Lewis X Inhibition.

Pucci, Michela; Gomes Ferreira, Inês; Malagolini, Nadia; Ferracin, Manuela; Dall'Olio, Fabio.

Afiliación

Pucci M; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), General Pathology Building, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.
Gomes Ferreira I; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), General Pathology Building, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.
Malagolini N; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), General Pathology Building, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.
Ferracin M; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), General Pathology Building, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.
Dall'Olio F; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), General Pathology Building, University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.

Int J Mol Sci ; 21(18)2020 Sep 08.

Article en En | MEDLINE | ID: mdl-32911675

Asunto(s)

Neoplasias del Colon/metabolismo; N-Acetilgalactosaminiltransferasas/metabolismo; Antígeno Sialil Lewis X/metabolismo; Línea Celular; Línea Celular Tumoral; Neoplasias del Colon/genética; Fucosiltransferasas/genética; Fucosiltransferasas/metabolismo; Glicosiltransferasas/metabolismo; Humanos; Antígeno Lewis X/metabolismo; N-Acetilgalactosaminiltransferasas/genética; Células Madre Neoplásicas/metabolismo; Células Madre Neoplásicas/fisiología; Oligosacáridos/genética; Oligosacáridos/inmunología; Oligosacáridos/metabolismo; Antígeno Sialil Lewis X/fisiología; Transfección; Células Tumorales Cultivadas

Palabras clave

Sda antigen; cancer stem cells; non-adherent growth; sialyl Lewis antigens; transcriptomic analysis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: N-Acetilgalactosaminiltransferasas / Neoplasias del Colon / Antígeno Sialil Lewis X Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza

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