Post-activation depression of primary afferents reevaluated in humans.
J Electromyogr Kinesiol
; 54: 102460, 2020 Oct.
Article
en En
| MEDLINE
| ID: mdl-32905963
Amplitude variation of Hoffmann Reflex (H-reflex) was used as a tool to investigate many neuronal networks. However, H-reflex itself is a subject to intrinsic changes including post-activation depression (P-AD). We aimed to investigate P-AD and its implication on motor control in humans. Upon tibial nerve stimulation in 23 healthy participants, peak-to-peak amplitude change of H-reflex was investigated using surface electromyography (SEMG) of soleus muscle. Variety of stimulus intensities, interstimulus intervals (ISIs), voluntary contraction levels/types and force recording were used to investigate the nature of P-AD. We have shown that P-AD was significantly stronger in the shorter ISIs. The only exception was the ISI of 200 msecs which had a weaker P-AD than some of the longer ISIs. Sudden muscle relaxation, on the other hand, further increased the effectiveness of the ongoing P-AD. Moreover, P-AD displayed its full effect with the first stimulus when there was no muscle contraction and was efficient to reduce the muscle force output by about 30%. These findings provide insight about the variations and mechanism of P-AD and could lead to improvements in diagnostic tools in neurological diseases.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Reflejo H
/
Inhibición Neural
/
Neuronas Aferentes
Límite:
Adult
/
Humans
Idioma:
En
Revista:
J Electromyogr Kinesiol
Asunto de la revista:
FISIOLOGIA
Año:
2020
Tipo del documento:
Article
País de afiliación:
Turquía
Pais de publicación:
Reino Unido