Introducing nitrogen atoms to amidoalkylindoles: potent and selective cannabinoid type 2 receptor agonists with improved aqueous solubility.

Ji, Yue-Yang; Wang, Zhi-Long; Pei, Fang-Ning; Shi, Jun-Jie; Li, Jiao-Jiao; Gunosewoyo, Hendra; Yang, Fan; Tang, Jie; Xie, Xin; Yu, Li-Fang

Ji, Yue-Yang; Wang, Zhi-Long; Pei, Fang-Ning; Shi, Jun-Jie; Li, Jiao-Jiao; Gunosewoyo, Hendra; Yang, Fan; Tang, Jie; Xie, Xin; Yu, Li-Fang.

Afiliación

Ji YY; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.
Wang ZL; CAS Key Laboratory of Receptor Research , National Center for Drug Screening , Shanghai Institute of Materia Medica , Chinese Academy of Sciences , 189 Guo Shou Jing Road , Shanghai 201203 , China . Email: xxie@simm.ac.cn.
Pei FN; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.
Shi JJ; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.
Li JJ; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.
Gunosewoyo H; School of Pharmacy and Biomedical Sciences , Faculty of Health Sciences , Curtin University , Bentley , Perth , WA 6102 , Australia.
Yang F; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.
Tang J; Shanghai Key Laboratory of Green Chemistry and Chemical Process , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China.
Xie X; CAS Key Laboratory of Receptor Research , National Center for Drug Screening , Shanghai Institute of Materia Medica , Chinese Academy of Sciences , 189 Guo Shou Jing Road , Shanghai 201203 , China . Email: xxie@simm.ac.cn.
Yu LF; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development , School of Chemistry and Molecular Engineering , East China Normal University , 3663 North Zhongshan Road , Shanghai 200062 , China . Email: lfyu@sat.ecnu.edu.cn.

Medchemcomm ; 10(12): 2131-2139, 2019 Dec 01.

Article en En | MEDLINE | ID: mdl-32904145

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Medchemcomm Año: 2019 Tipo del documento: Article Pais de publicación: Reino Unido

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