Your browser doesn't support javascript.
loading
Development of a tool to assess evidence for causality in studies implicating sink drains as a reservoir for hospital-acquired gammaproteobacterial infection.
Volling, C; Thomas, S; Johnstone, J; Maltezou, H C; Mertz, D; Stuart, R; Jamal, Alainna J; Kandel, C; Ahangari, N; Coleman, B L; McGeer, A.
Afiliación
  • Volling C; Mount Sinai Hospital, Toronto, ON, Canada; University of Toronto, Toronto, ON, Canada. Electronic address: cheryl.volling@mail.utoronto.ca.
  • Thomas S; Mount Sinai Hospital, Toronto, ON, Canada.
  • Johnstone J; Mount Sinai Hospital, Toronto, ON, Canada; University of Toronto, Toronto, ON, Canada.
  • Maltezou HC; National Public Health Organization, Athens, Greece.
  • Mertz D; Hamilton Health Sciences, Hamilton, ON, Canada; McMaster University, Hamilton, ON, Canada.
  • Stuart R; Monash Health, Clayton, Victoria, Australia; Monash University, Clayton, Victoria, Australia.
  • Jamal AJ; Mount Sinai Hospital, Toronto, ON, Canada; University of Toronto, Toronto, ON, Canada.
  • Kandel C; Mount Sinai Hospital, Toronto, ON, Canada; University of Toronto, Toronto, ON, Canada.
  • Ahangari N; Mount Sinai Hospital, Toronto, ON, Canada.
  • Coleman BL; Mount Sinai Hospital, Toronto, ON, Canada; University of Toronto, Toronto, ON, Canada.
  • McGeer A; Mount Sinai Hospital, Toronto, ON, Canada; University of Toronto, Toronto, ON, Canada.
J Hosp Infect ; 106(3): 454-464, 2020 11.
Article en En | MEDLINE | ID: mdl-32898614
BACKGROUND: Decades of studies document an association between Gammaproteobacteria in sink drains and hospital-acquired infections, but the evidence for causality is unclear. AIM: We aimed to develop a tool to assess the quality of evidence for causality in research studies that implicate sink drains as reservoirs for hospital-acquired Gammaproteobacterial infections. METHODS: We used a modified Delphi process with recruited experts in hospital epidemiology to develop this tool from a pre-existing causal assessment application. FINDINGS: Through four rounds of feedback and revision we developed the 'Modified CADDIS Tool for Causality Assessment of Sink Drains as a Reservoir for Hospital-Acquired Gammaproteobacterial Infection or Colonization'. In tests of tool application to published literature during development, mean percent agreement ranged from 46.7% to 87.5%, and the Gwet's AC1 statistic (adjusting for chance agreement) ranged from 0.13 to 1.0 (median 68.1). Areas of disagreement were felt to result from lack of a priori knowledge of causal pathways from sink drains to patients and uncertain influence of co-interventions to prevent organism acquisition. Modifications were made until consensus was achieved that further iterations would not improve the tool. When the tool was applied to 44 articles by two independent reviewers in an ongoing systematic review, percent agreement ranged from 93% to 98%, and the Gwet's AC1 statistic was 0.91-0.97. CONCLUSION: The modified causality tool was useful for evaluating studies that implicate sink drains as reservoirs for hospital-acquired infections and may help guide the conduct and reporting of future research.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Programas Informáticos / Reservorios de Enfermedades / Infección Hospitalaria / Contaminación de Equipos / Infecciones por Bacterias Gramnegativas / Equipos y Suministros de Hospitales Tipo de estudio: Etiology_studies / Systematic_reviews Límite: Humans Idioma: En Revista: J Hosp Infect Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Programas Informáticos / Reservorios de Enfermedades / Infección Hospitalaria / Contaminación de Equipos / Infecciones por Bacterias Gramnegativas / Equipos y Suministros de Hospitales Tipo de estudio: Etiology_studies / Systematic_reviews Límite: Humans Idioma: En Revista: J Hosp Infect Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido