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Morphometric and traditional frailty assessment in transcatheter aortic valve implantation.
Waduud, Mohammed A; Giannoudi, Marilena; Drozd, Michael; Sucharitkul, Penelope P J; Slater, Thomas A; Blackman, Daniel J; Scott, David J A.
Afiliación
  • Waduud MA; Leeds Vascular Institute, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust.
  • Giannoudi M; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds.
  • Drozd M; Leeds Vascular Institute, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust.
  • Sucharitkul PPJ; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds.
  • Slater TA; Leeds Vascular Institute, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust.
  • Blackman DJ; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds.
  • Scott DJA; Department of Cardiology, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
J Cardiovasc Med (Hagerstown) ; 21(10): 779-786, 2020 Oct.
Article en En | MEDLINE | ID: mdl-32898382
OBJECTIVES: Frailty is common amongst patients undergoing transcatheter aortic valve implantation (TAVI). The aim of this study was to determine the prognostic relevance of newer objective and traditional measures of frailty after TAVI. METHODS: Consecutive patients were identified from the Leeds Teaching Hospitals Trust TAVI database. Frailty was quantified objectively by measuring the total psoas muscle area (TPMA) on routine computer tomography scans and compared against Canadian Study of Health and Aging Clinical Frailty Score, Katz Index of independence in activities of daily living and Clinician Estimated Poor Mobility. Postintervention morbidity and mortality were examined between these scoring systems. RESULTS: The current study included 420 patients who had undergone TAVI between January 2013 and December 2015. Median clinical follow-up was 4.0 years (interquartile range 2.9-5.0). Standardized measurements of the TPMA were not associated with either postintervention morbidity or mortality. Only the Canadian Study of Health and Aging Clinical Frailty Score was associated with hospital stay (adjusted regression coefficient 0.70, 95% confidence interval 0.04-1.36, P = 0.038) and overall all-cause mortality (adjusted regression coefficient 1.26, 95% confidence interval 1.05-1.50, P = 0.013). There were no significant correlations between TPMA and any of the traditional frailty tools. CONCLUSION: We demonstrate TPMA to be a poor measure of patient frailty when compared with traditional methods of assessment which failed to predict postintervention outcomes. Furthermore, morphometric sarcopaenia correlated poorly with established measures of frailty.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Válvula Aórtica / Estenosis de la Válvula Aórtica / Evaluación Geriátrica / Anciano Frágil / Músculos Psoas / Sarcopenia / Reemplazo de la Válvula Aórtica Transcatéter / Fragilidad Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Aged / Aged80 / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: J Cardiovasc Med (Hagerstown) Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Válvula Aórtica / Estenosis de la Válvula Aórtica / Evaluación Geriátrica / Anciano Frágil / Músculos Psoas / Sarcopenia / Reemplazo de la Válvula Aórtica Transcatéter / Fragilidad Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Aged / Aged80 / Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: J Cardiovasc Med (Hagerstown) Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos