Toxicogenomic study to identify potential signaling alterations related to nasal inflammatory damages induced by diesel exhaust particles in primary human nasal epithelial cells.

Kim, Hyun Soo; Kim, Hyo Jeong; Kim, Nahyun; Song, Jae-Jun; Son, Bu-Soon; Yang, Jun Hyuek; Lee, Cheol Min; Park, Moo Kyun; Seo, Young Rok

Kim, Hyun Soo; Kim, Hyo Jeong; Kim, Nahyun; Song, Jae-Jun; Son, Bu-Soon; Yang, Jun Hyuek; Lee, Cheol Min; Park, Moo Kyun; Seo, Young Rok.

Afiliación

Kim HS; Department of Life Science, Dongguk University Biomedi Campus, Gyeonggi-do, Republic of Korea; Institute of Environmental Medicine, Dongguk University Biomedi Campus, Gyeonggi-do, Republic of Korea.
Kim HJ; Department of Life Science, Dongguk University Biomedi Campus, Gyeonggi-do, Republic of Korea; Institute of Environmental Medicine, Dongguk University Biomedi Campus, Gyeonggi-do, Republic of Korea.
Kim N; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.
Song JJ; Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Republic of Korea.
Son BS; Department of Environmental Health Science, Soonchunhyang University, Asan, South Korea.
Yang JH; Department of Life Science, Dongguk University Biomedi Campus, Gyeonggi-do, Republic of Korea; Institute of Environmental Medicine, Dongguk University Biomedi Campus, Gyeonggi-do, Republic of Korea.
Lee CM; Department of Chemical and Biological Engineering, Seokyeong University, Seoul, Republic of Korea.
Park MK; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address: aseptic@snu.ac.kr.
Seo YR; Department of Life Science, Dongguk University Biomedi Campus, Gyeonggi-do, Republic of Korea; Institute of Environmental Medicine, Dongguk University Biomedi Campus, Gyeonggi-do, Republic of Korea. Electronic address: seoyr@dongguk.edu.

Toxicol In Vitro ; 69: 104994, 2020 Dec.

Article en En | MEDLINE | ID: mdl-32891722

Asunto(s)

Células Epiteliales/efectos de los fármacos; Mucosa Nasal/citología; Transcriptoma/efectos de los fármacos; Emisiones de Vehículos/toxicidad; Células Cultivadas; Factores Estimulantes de Colonias/genética; Células Epiteliales/metabolismo; Humanos; Inflamación/genética; Interleucina-8/genética; Metaloproteinasa 1 de la Matriz/genética; Transducción de Señal/efectos de los fármacos; Toxicogenética; Factor A de Crecimiento Endotelial Vascular/genética

Palabras clave

Diesel exhaust particle; Human primary nasal epithelial cell; Pathway analysis; Toxicogenomics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Emisiones de Vehículos / Células Epiteliales / Transcriptoma / Mucosa Nasal Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Toxicol In Vitro Asunto de la revista: TOXICOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido

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