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Brain Characteristics Noted Prior to and Following Cranial Orthotic Treatment.
DeGrazia, Michele; Ahtam, Banu; Rogers-Vizena, Carolyn R; Proctor, Mark; Porter, Courtney; Vyas, Rutvi; Laurentys, Cynthia T; Bergling, Emily; McLaughlin, Kara; Grant, Patricia Ellen.
Afiliación
  • DeGrazia M; Cardiovascular and Critical Care, Boston Children's Hospital, Boston, MA, USA.
  • Ahtam B; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Rogers-Vizena CR; Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Proctor M; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Porter C; Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Vyas R; Fetal-Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA, USA.
  • Laurentys CT; Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, MA, USA.
  • Bergling E; Department of Surgery, Harvard Medical School, Boston, MA, USA.
  • McLaughlin K; Department of Neurosurgery, Boston Children's Hospital, Boston, MA, USA.
  • Grant PE; Department of Neurosurgery, Harvard Medical School, Boston, MA, USA.
Child Neurol Open ; 7: 2329048X20949769, 2020.
Article en En | MEDLINE | ID: mdl-32884966
OBJECTIVE: This case report aims to assess a potential association between cranial asymmetry, brain deformation, and associated developmental delay. STUDY DESIGN: Two infants born at ≥37 weeks pursuing cranial orthotic treatment for severe Deformational Plagiocephaly (DP) (cranial vault asymmetry index >8.75%) underwent developmental assessment using Mullen Scales of Early Learning (MSEL) and non-sedated brain structural and diffusion magnetic resonance imaging (MRI) prior to and following cranial orthotic treatment. RESULTS: In both infants with DP, tractography results revealed alterations in the white matter pathways of the brain. Both infants also had low to low/normal visual receptivity and fine motor skills. After cranial orthotic treatment, cranial asymmetry improved but did not completely resolve, tractography demonstrated a change toward normalized white matter pathways, and visual receptivity and fine motor skills improved. CONCLUSIONS: These preliminary findings suggest a potential link between DP, altered brain structures, and developmental assessment. Further investigation with a larger sample is warranted.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Child Neurol Open Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Child Neurol Open Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos