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Discovery of potent small molecule PROTACs targeting mutant EGFR.
Zhao, Hong-Yi; Yang, Xue-Yan; Lei, Hao; Xi, Xiao-Xiao; Lu, She-Min; Zhang, Jun-Jie; Xin, Minhang; Zhang, San-Qi.
Afiliación
  • Zhao HY; Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, PR China.
  • Yang XY; Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, PR China.
  • Lei H; Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, PR China.
  • Xi XX; Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, PR China.
  • Lu SM; School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, PR China.
  • Zhang JJ; School of Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710049, PR China.
  • Xin M; Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, PR China. Electronic address: xmhcpu@163.com.
  • Zhang SQ; Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, PR China. Electronic address: sqzhang@xjtu.edu.cn.
Eur J Med Chem ; 208: 112781, 2020 Dec 15.
Article en En | MEDLINE | ID: mdl-32883633
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Purinas / Inhibidores de Proteínas Quinasas / Proteolisis / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2020 Tipo del documento: Article Pais de publicación: Francia
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Purinas / Inhibidores de Proteínas Quinasas / Proteolisis / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2020 Tipo del documento: Article Pais de publicación: Francia