Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves.

Frasca, Antonio; Xue, Yingfei; Kossar, Alexander P; Keeney, Samuel; Rock, Christopher; Zakharchenko, Andrey; Streeter, Matthew; Gorman, Robert C; Grau, Juan B; George, Isaac; Bavaria, Joseph E; Krieger, Abba; Spiegel, David A; Levy, Robert J; Ferrari, Giovanni

Frasca, Antonio; Xue, Yingfei; Kossar, Alexander P; Keeney, Samuel; Rock, Christopher; Zakharchenko, Andrey; Streeter, Matthew; Gorman, Robert C; Grau, Juan B; George, Isaac; Bavaria, Joseph E; Krieger, Abba; Spiegel, David A; Levy, Robert J; Ferrari, Giovanni.

Afiliación

Frasca A; Department of Surgery, Columbia University, New York, New York.
Xue Y; Department of Surgery, Columbia University, New York, New York.
Kossar AP; Department of Surgery, Columbia University, New York, New York.
Keeney S; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Rock C; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Zakharchenko A; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Streeter M; Department of Chemistry, Yale University, New Haven, Connecticut.
Gorman RC; Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
Grau JB; Ottawa Heart Institute, Ottawa, Ontario, Canada.
George I; Department of Surgery, Columbia University, New York, New York.
Bavaria JE; Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
Krieger A; Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
Spiegel DA; Department of Chemistry, Yale University, New Haven, Connecticut.
Levy RJ; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Ferrari G; Department of Surgery, Columbia University, New York, New York.

JACC Basic Transl Sci ; 5(8): 755-766, 2020 Aug.

Article en En | MEDLINE | ID: mdl-32875167

Palabras clave

AGE, advanced glycation end product; BHV, bioprosthetic heart valve; BP, bovine pericardium; CML, N-carboxymethyl-lysine; EOA, effective orifice area; HSA, human serum albumin; IHC, immunohistochemistry; PBS, phosphate-buffered saline; SAVR, surgical aortic valve replacement; SHG, second harmonic generation; SVD, structural valve degeneration; TAVR, transcatheter aortic valve replacement; advanced glycation end products; aortic valve disease; biomaterial; bioprosthetic heart valve

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: JACC Basic Transl Sci Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

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