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Additional pharmacological activity of I-modulia and generation of two newly designed extracts of Aquaphilus dolomiae culture for dermocosmetic actives.
Nguyen, T; Chol, B; Maitre, M; Ravard-Helffer, K; Farinole, F; Lestienne, F; Castex-Rizzi, N.
Afiliación
  • Nguyen T; Pierre Fabre Dermocosmétique, Biotechnology, Toulouse cedex, France.
  • Chol B; Centre d'Immunologie Pierre Fabre, St-Julien-en-Genevois, France.
  • Maitre M; Pierre Fabre Dermocosmétique, Biotechnology, Toulouse cedex, France.
  • Ravard-Helffer K; Pierre Fabre Dermocosmétique, Biotechnology, Toulouse cedex, France.
  • Farinole F; Pierre Fabre Dermocosmétique, Biotechnology, Toulouse cedex, France.
  • Lestienne F; Pierre Fabre Dermocosmétique, Pharmacology Division, Toulouse cedex, France.
  • Castex-Rizzi N; Pierre Fabre Dermocosmétique, Pharmacology Division, Toulouse cedex, France.
J Eur Acad Dermatol Venereol ; 34 Suppl 5: 27-29, 2020 Aug.
Article en En | MEDLINE | ID: mdl-32870555
Aquaphilus dolomiae (AD) is a unique isolate from Avène Thermal Spring Water. I-Modulia, the first biotech extract from culture of AD, was used as immune modulator in Th2 inflammatory models. In this short publication, firstly we describe generation of two AD de novo extracts specifically designed for repairing and for neuroinflammation modulation activities which will be described, respectively, in two other articles in this supplement. Finally, for I-modulia, we describe new data on inhibition of human mast cell degranulation in vitro and its effect on substance P-induced neurogenic inflammation on ex vivo human skin explants.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mastocitos / Neisseriaceae Límite: Humans Idioma: En Revista: J Eur Acad Dermatol Venereol Asunto de la revista: DERMATOLOGIA / DOENCAS SEXUALMENTE TRANSMISSIVEIS Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mastocitos / Neisseriaceae Límite: Humans Idioma: En Revista: J Eur Acad Dermatol Venereol Asunto de la revista: DERMATOLOGIA / DOENCAS SEXUALMENTE TRANSMISSIVEIS Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido