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PET and MRI guided adaptive radiotherapy: Rational, feasibility and benefit.
Thureau, S; Briens, A; Decazes, P; Castelli, J; Barateau, A; Garcia, R; Thariat, J; de Crevoisier, R.
Afiliación
  • Thureau S; Département de radiothérapie et de physique médicale, centre Henri-Becquerel, QuantIF EA 4108, université de Rouen, 76000 Rouen, France. Electronic address: sebastien.thureau@chb.unicancer.fr.
  • Briens A; Département de radiothérapie, centre Eugène-Marquis, rue de la Bataille-Flandres-Dunkerque, CS 44229, 35042 Rennes cedex, France.
  • Decazes P; Département de médecine nucléaire, center Henri-Becquerel, QuantIF EA 4108, université de Rouen, Rouen, France.
  • Castelli J; Département de radiothérapie, centre Eugène Marquis, rue de la Bataille-Flandres-Dunkerque, CS 44229, 35042 Rennes cedex, France; CLCC Eugène Marquis, Inserm, LTSI-UMR 1099, université de Rennes, 35000 Rennes, France.
  • Barateau A; Département de radiothérapie, centre Eugène Marquis, rue de la Bataille-Flandres-Dunkerque, CS 44229, 35042 Rennes cedex, France; CLCC Eugène Marquis, Inserm, LTSI-UMR 1099, université de Rennes, 35000 Rennes, France.
  • Garcia R; Service de physique médicale, institut Sainte-Catherine, 84918 Avignon, France.
  • Thariat J; Department of radiation oncology, centre François-Baclesse, 14000 Caen, France; Laboratoire de physique corpusculaire IN2P3/ENSICAEN-UMR6534-Unicaen-Normandie université, 14000 Caen, France; ARCHADE Research Community, 14000 Caen, France.
  • de Crevoisier R; Département de radiothérapie, centre Eugène-Marquis, rue de la Bataille-Flandres-Dunkerque, CS 44229, 35042 Rennes cedex, France; CLCC Eugène Marquis, Inserm, LTSI-UMR 1099, université de Rennes, 35000 Rennes, France.
Cancer Radiother ; 24(6-7): 635-644, 2020 Oct.
Article en En | MEDLINE | ID: mdl-32859466
Adaptive radiotherapy (ART) corresponds to various replanning strategies aiming to correct for anatomical variations occurring during the course of radiotherapy. The goal of the article was to report the rational, feasibility and benefit of using PET and/or MRI to guide this ART strategy in various tumor localizations. The anatomical modifications defined by scanner taking into account tumour mobility and volume variation are not always sufficient to optimise treatment. The contribution of functional imaging by PET or the precision of soft tissue by MRI makes it possible to consider optimized ART. Today, the most important data for both PET and MRI are for lung, head and neck, cervical and prostate cancers. PET and MRI guided ART appears feasible and safe, however in a very limited clinical experience. Phase I/II studies should be therefore performed, before proposing cost-effectiveness comparisons in randomized trials and before using the approach in routine practice.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Tomografía de Emisión de Positrones / Radioterapia Guiada por Imagen / Neoplasias Tipo de estudio: Clinical_trials Límite: Female / Humans / Male Idioma: En Revista: Cancer Radiother Asunto de la revista: NEOPLASIAS / RADIOTERAPIA Año: 2020 Tipo del documento: Article Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Tomografía de Emisión de Positrones / Radioterapia Guiada por Imagen / Neoplasias Tipo de estudio: Clinical_trials Límite: Female / Humans / Male Idioma: En Revista: Cancer Radiother Asunto de la revista: NEOPLASIAS / RADIOTERAPIA Año: 2020 Tipo del documento: Article Pais de publicación: Francia