A natural product biflavonoid scaffold with anti-tryptase activity.

Fazio, Nicholas F; Russell, Michael H; Flinders, Steven M; Gardner, Colin J; Webster, Jace B; Hansen, Marc D H

Fazio, Nicholas F; Russell, Michael H; Flinders, Steven M; Gardner, Colin J; Webster, Jace B; Hansen, Marc D H.

Afiliación

Fazio NF; Department of Physiology and Developmental Biology, Brigham Young University, 4005 LSB, Provo, UT, 84602, USA.
Russell MH; Department of Physiology and Developmental Biology, Brigham Young University, 4005 LSB, Provo, UT, 84602, USA.
Flinders SM; Department of Physiology and Developmental Biology, Brigham Young University, 4005 LSB, Provo, UT, 84602, USA.
Gardner CJ; Department of Physiology and Developmental Biology, Brigham Young University, 4005 LSB, Provo, UT, 84602, USA.
Webster JB; Department of Physiology and Developmental Biology, Brigham Young University, 4005 LSB, Provo, UT, 84602, USA.
Hansen MDH; Department of Physiology and Developmental Biology, Brigham Young University, 4005 LSB, Provo, UT, 84602, USA. marchansen@byu.edu.

Naunyn Schmiedebergs Arch Pharmacol ; 394(1): 107-115, 2021 01.

Article en En | MEDLINE | ID: mdl-32840651

Asunto(s)

Biflavonoides/farmacología; Productos Biológicos/farmacología; Triptasas/antagonistas & inhibidores; Biflavonoides/química; Productos Biológicos/química; Simulación del Acoplamiento Molecular; Relación Estructura-Actividad; Triptasas/metabolismo

Palabras clave

Biflavonoid; Computational screen; Mast cell; Tryptase

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Productos Biológicos / Biflavonoides / Triptasas Tipo de estudio: Prognostic_studies Idioma: En Revista: Naunyn Schmiedebergs Arch Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania

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