Biochemical Characterization and Crystal Structure of a Novel NAD<sup>+</sup>-Dependent Isocitrate Dehydrogenase from <i>Phaeodactylum tricornutum</i>.

Huang, Shi-Ping; Zhou, Lu-Chun; Wen, Bin; Wang, Peng; Zhu, Guo-Ping

Biochemical Characterization and Crystal Structure of a Novel NAD⁺-Dependent Isocitrate Dehydrogenase from Phaeodactylum tricornutum.

Huang, Shi-Ping; Zhou, Lu-Chun; Wen, Bin; Wang, Peng; Zhu, Guo-Ping.

Afiliación

Huang SP; Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases and Key Laboratory of Biomedicine in Gene Diseases and Health of Anhui Higher Education Institutes, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.
Zhou LC; Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases and Key Laboratory of Biomedicine in Gene Diseases and Health of Anhui Higher Education Institutes, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.
Wen B; Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases and Key Laboratory of Biomedicine in Gene Diseases and Health of Anhui Higher Education Institutes, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.
Wang P; Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases and Key Laboratory of Biomedicine in Gene Diseases and Health of Anhui Higher Education Institutes, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.
Zhu GP; Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases and Key Laboratory of Biomedicine in Gene Diseases and Health of Anhui Higher Education Institutes, College of Life Sciences, Anhui Normal University, Wuhu 241000, China.

Int J Mol Sci ; 21(16)2020 Aug 18.

Article en En | MEDLINE | ID: mdl-32824636

Asunto(s)

Diatomeas/enzimología; Isocitrato Deshidrogenasa/química; Regulación Alostérica; Sitio Alostérico; Cristalografía por Rayos X; Motivos EF Hand; Isocitrato Deshidrogenasa/metabolismo; Isocitratos/química; Isocitratos/metabolismo; NAD/química; NAD/metabolismo

Palabras clave

Phaeodactylum tricornutum; biochemical characterization; crystal structure; isocitrate dehydrogenase; kinetics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diatomeas / Isocitrato Deshidrogenasa Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

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