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Addiction to protein kinase CÉ© due to PRKCI gene amplification can be exploited for an aptamer-based targeted therapy in ovarian cancer.
Rehmani, Hina; Li, Yue; Li, Tao; Padia, Ravi; Calbay, Ozlem; Jin, Lingtao; Chen, Huijun; Huang, Shuang.
Afiliación
  • Rehmani H; Department of Biochemistry and Cancer Biology, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
  • Li Y; Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL, 32610, USA.
  • Li T; Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL, 32610, USA.
  • Padia R; Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL, 32610, USA.
  • Calbay O; Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL, 32610, USA.
  • Jin L; Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL, 32610, USA.
  • Chen H; Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, FL, 32610, USA.
  • Huang S; Department of Gynecology and Obstetrics, Zhongnan Hospital of Wuhan University, 430071, Wuhan, Hubei, China. karrel@sina.com.
Signal Transduct Target Ther ; 5(1): 140, 2020 08 21.
Article en En | MEDLINE | ID: mdl-32820156
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Proteína Quinasa C / Amplificación de Genes / Aptámeros de Nucleótidos / Isoenzimas / Proteínas de Neoplasias Límite: Animals / Female / Humans Idioma: En Revista: Signal Transduct Target Ther Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Proteína Quinasa C / Amplificación de Genes / Aptámeros de Nucleótidos / Isoenzimas / Proteínas de Neoplasias Límite: Animals / Female / Humans Idioma: En Revista: Signal Transduct Target Ther Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido