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The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism.
Stanisich, Jessica J; Zyla, Dawid S; Afanasyev, Pavel; Xu, Jingwei; Kipp, Anne; Olinger, Eric; Devuyst, Olivier; Pilhofer, Martin; Boehringer, Daniel; Glockshuber, Rudi.
Afiliación
  • Stanisich JJ; Institute of Molecular Biology & Biophysics, ETH Zurich, Zurich, Switzerland.
  • Zyla DS; Institute of Molecular Biology & Biophysics, ETH Zurich, Zurich, Switzerland.
  • Afanasyev P; Cryo-​EM Knowledge Hub (CEMK), ETH Zurich, Zurich, Switzerland.
  • Xu J; Institute of Molecular Biology & Biophysics, ETH Zurich, Zurich, Switzerland.
  • Kipp A; Institute of Physiology, University of Zurich, Zurich, Switzerland.
  • Olinger E; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Central Parkway, Newcastle upon Tyne, United Kingdom.
  • Devuyst O; Institute of Physiology, University of Zurich, Zurich, Switzerland.
  • Pilhofer M; Division of Nephrology, UCLouvain Medical School, Brussels, Belgium.
  • Boehringer D; Institute of Molecular Biology & Biophysics, ETH Zurich, Zurich, Switzerland.
  • Glockshuber R; Cryo-​EM Knowledge Hub (CEMK), ETH Zurich, Zurich, Switzerland.
Elife ; 92020 08 20.
Article en En | MEDLINE | ID: mdl-32815518

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Uromodulina Límite: Humans Idioma: En Revista: Elife Año: 2020 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Uromodulina Límite: Humans Idioma: En Revista: Elife Año: 2020 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido