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Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time.
Barnes, Kayla G; Lachenauer, Anna E; Nitido, Adam; Siddiqui, Sameed; Gross, Robin; Beitzel, Brett; Siddle, Katherine J; Freije, Catherine A; Dighero-Kemp, Bonnie; Mehta, Samar B; Carter, Amber; Uwanibe, Jessica; Ajogbasile, Fehintola; Olumade, Testimony; Odia, Ikponmwosa; Sandi, John Demby; Momoh, Mambu; Metsky, Hayden C; Boehm, Chloe K; Lin, Aaron E; Kemball, Molly; Park, Daniel J; Branco, Luis; Boisen, Matt; Sullivan, Brian; Amare, Mihret F; Tiamiyu, Abdulwasiu B; Parker, Zahra F; Iroezindu, Michael; Grant, Donald S; Modjarrad, Kayvon; Myhrvold, Cameron; Garry, Robert F; Palacios, Gustavo; Hensley, Lisa E; Schaffner, Stephen F; Happi, Christian T; Colubri, Andres; Sabeti, Pardis C.
Afiliación
  • Barnes KG; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. kbarnes@broadinstitute.org.
  • Lachenauer AE; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, USA. kbarnes@broadinstitute.org.
  • Nitido A; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK. kbarnes@broadinstitute.org.
  • Siddiqui S; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. annalach@stanford.edu.
  • Gross R; Stanford University School of Medicine, Stanford, California, USA. annalach@stanford.edu.
  • Beitzel B; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, 02139, USA.
  • Siddle KJ; Ph.D. Program in Virology, Division of Medical Sciences, Harvard Medical School, Boston, Massachusetts, 02115, USA.
  • Freije CA; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Dighero-Kemp B; Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Mehta SB; Integrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, Maryland, USA.
  • Carter A; Center for Genome Sciences, The United States Army Medical Research Institute for Infectious Disease, 1425 Porter Street, Fort Detrick, Maryland, 21702, USA.
  • Uwanibe J; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Ajogbasile F; Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.
  • Olumade T; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Odia I; Ph.D. Program in Virology, Division of Medical Sciences, Harvard Medical School, Boston, Massachusetts, 02115, USA.
  • Sandi JD; Integrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, Maryland, USA.
  • Momoh M; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Metsky HC; Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
  • Boehm CK; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Lin AE; African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer's University, Ede, Osun State, Nigeria.
  • Kemball M; Department of Biological Sciences, College of Natural Sciences, Redeemer's University, Ede, Osun State, Nigeria.
  • Park DJ; African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer's University, Ede, Osun State, Nigeria.
  • Branco L; Department of Biological Sciences, College of Natural Sciences, Redeemer's University, Ede, Osun State, Nigeria.
  • Boisen M; African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer's University, Ede, Osun State, Nigeria.
  • Sullivan B; Department of Biological Sciences, College of Natural Sciences, Redeemer's University, Ede, Osun State, Nigeria.
  • Amare MF; Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria.
  • Tiamiyu AB; African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer's University, Ede, Osun State, Nigeria.
  • Parker ZF; Viral Hemorrhagic Fever Program, Kenema Government Hospital, Kenema, Sierra Leone.
  • Iroezindu M; African Center of Excellence for Genomics of Infectious Disease (ACEGID), Redeemer's University, Ede, Osun State, Nigeria.
  • Grant DS; Viral Hemorrhagic Fever Program, Kenema Government Hospital, Kenema, Sierra Leone.
  • Modjarrad K; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Myhrvold C; Department of Electrical Engineering and Computer Science, MIT, Cambridge, Massachusetts, 02139, USA.
  • Garry RF; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Palacios G; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Hensley LE; Ph.D. Program in Virology, Division of Medical Sciences, Harvard Medical School, Boston, Massachusetts, 02115, USA.
  • Schaffner SF; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Happi CT; Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.
  • Colubri A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Sabeti PC; Zalgen Labs, Germantown, Maryland, USA.
Nat Commun ; 11(1): 4131, 2020 08 17.
Article en En | MEDLINE | ID: mdl-32807807
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fiebre Hemorrágica Ebola / Ebolavirus / Fiebre de Lassa / Virus Lassa Tipo de estudio: Diagnostic_studies / Guideline Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fiebre Hemorrágica Ebola / Ebolavirus / Fiebre de Lassa / Virus Lassa Tipo de estudio: Diagnostic_studies / Guideline Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido