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A novel biparatopic hybrid antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy.
Miao, Xiaoniu; Luo, Yi; Huang, Xi; Lee, Suki M Y; Yuan, Zhijun; Tang, Yongzhou; Chen, Liandi; Wang, Chao; Wu, Fan; Xu, Yifeng; Jiang, Wenchao; Gao, Wei; Song, Xuedong; Yan, Yao; Pang, Tuling; Chen, Cheng; Zou, Yuefeng; Fu, Weihui; Wan, Liping; Gilbert-Jaramillo, Javier; Knight, Michael; Tan, Tiong Kit; Rijal, Pramila; Townsend, Alain; Sun, Joanne; Liu, Xiaolin; James, William; Tsun, Andy; Xu, Yingda.
Afiliación
  • Miao X; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Luo Y; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Huang X; The Fifth Affiliated Hospital, Sun Yat-Sen University , Zhuhai, China.
  • Lee SMY; New Drug Discovery and Development, Hong Kong Science and Technology Park , China.
  • Yuan Z; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Tang Y; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Chen L; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Wang C; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Wu F; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Xu Y; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Jiang W; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Gao W; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Song X; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Yan Y; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Pang T; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Chen C; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Zou Y; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Fu W; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Wan L; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Gilbert-Jaramillo J; Sir William Dunn School of Pathology, University of Oxford , Oxford, UK.
  • Knight M; Sir William Dunn School of Pathology, University of Oxford , Oxford, UK.
  • Tan TK; Centre for Translational Immunology, Chinese Academy of Medical Sciences Oxford Institute, University of Oxford , Oxford, UK.
  • Rijal P; Centre for Translational Immunology, Chinese Academy of Medical Sciences Oxford Institute, University of Oxford , Oxford, UK.
  • Townsend A; Centre for Translational Immunology, Chinese Academy of Medical Sciences Oxford Institute, University of Oxford , Oxford, UK.
  • Sun J; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Liu X; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • James W; Sir William Dunn School of Pathology, University of Oxford , Oxford, UK.
  • Tsun A; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
  • Xu Y; New Drug Discovery and Development, Biotheus Inc , Zhuhai, China.
MAbs ; 12(1): 1804241, 2020.
Article en En | MEDLINE | ID: mdl-32804015
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones por Coronavirus / Peptidil-Dipeptidasa A / Anticuerpos Neutralizantes / Pandemias / Betacoronavirus / Anticuerpos Antivirales Límite: Humans Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neumonía Viral / Infecciones por Coronavirus / Peptidil-Dipeptidasa A / Anticuerpos Neutralizantes / Pandemias / Betacoronavirus / Anticuerpos Antivirales Límite: Humans Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos