An inducible circular RNA circKcnt2 inhibits ILC3 activation to facilitate colitis resolution.

Liu, Benyu; Ye, Buqing; Zhu, Xiaoxiao; Yang, Liuliu; Li, Huimu; Liu, Nian; Zhu, Pingping; Lu, Tiankun; He, Luyun; Tian, Yong; Fan, Zusen

Liu, Benyu; Ye, Buqing; Zhu, Xiaoxiao; Yang, Liuliu; Li, Huimu; Liu, Nian; Zhu, Pingping; Lu, Tiankun; He, Luyun; Tian, Yong; Fan, Zusen.

Afiliación

Liu B; Key Laboratory of Infection and Immunity of CAS, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Ye B; Key Laboratory of Infection and Immunity of CAS, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Zhu X; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Yang L; Key Laboratory of Infection and Immunity of CAS, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Li H; University of Chinese Academy of Sciences, 100049, Beijing, China.
Liu N; Key Laboratory of Infection and Immunity of CAS, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Zhu P; University of Chinese Academy of Sciences, 100049, Beijing, China.
Lu T; Key Laboratory of Infection and Immunity of CAS, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
He L; University of Chinese Academy of Sciences, 100049, Beijing, China.
Tian Y; Key Laboratory of Infection and Immunity of CAS, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Fan Z; Key Laboratory of Infection and Immunity of CAS, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.

Nat Commun ; 11(1): 4076, 2020 08 14.

Article en En | MEDLINE | ID: mdl-32796851

Asunto(s)

Colitis/inmunología; Colitis/metabolismo; Linfocitos/metabolismo; Canales de potasio activados por Sodio/metabolismo; ARN Circular/metabolismo; Animales; Colitis/patología; Proteínas de Unión al ADN/genética; Modelos Animales de Enfermedad; Femenino; Proteínas de Homeodominio/genética; Homeostasis; Humanos; Inmunidad Innata; Inflamación/inmunología; Inflamación/patología; Intestinos/patología; Ratones; Ratones Endogámicos C57BL; Ratones Endogámicos ICR; Ratones Noqueados; Canales de potasio activados por Sodio/genética; ARN Circular/genética; ARN no Traducido/genética; ARN no Traducido/metabolismo; Factores de Transcripción/genética

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos / Colitis / Canales de potasio activados por Sodio / ARN Circular Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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