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Effect of poly (γ-glutamic acid)/tricalcium phosphate (γ-PGA/TCP) composite for dentin remineralization in vitro.
Su, Qing-Qing; Zhang, Chao; Mai, Sui; Lin, Huan-Cai; Zhi, Qing-Hui.
Afiliación
  • Su QQ; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University & Guangdong Provincial Key Laboratory of Stomatology.
  • Zhang C; Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instruments, School of Engineering, Sun Yat-Sen University.
  • Mai S; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University & Guangdong Provincial Key Laboratory of Stomatology.
  • Lin HC; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University & Guangdong Provincial Key Laboratory of Stomatology.
  • Zhi QH; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University & Guangdong Provincial Key Laboratory of Stomatology.
Dent Mater J ; 40(1): 26-34, 2021 Jan 31.
Article en En | MEDLINE | ID: mdl-32779606
The poly (γ-glutamic acid)/tricalcium phosphate (γ-PGA/TCP) composite was fabricated as a novel biomineralization material function in preventing caries. Demineralized bovine dentin specimens were prepared and randomly divided into 5 groups (i. α-TCP, ⅱ. γ-PGA, ⅲ. γ-PGA/TCP, ⅳ. CPP-ACP, and ⅴ. deionized water) and subjected to 14 days of pH cycling. Remineralization ability was evaluated by lesion depth, mineral loss and microhardness. The morphology of dentin depositions was observed with scanning electron microscope (SEM), the crystal structure was determined by X-ray diffraction (XRD), and the wettability was tested by contact angle measurements. ANOVA revealed specimens treated by γ-PGA/TCP presented the statistically least lesion depth (p<0.01) and mineral loss (p<0.001), and the highest hardness (p<0.001). SEM revealed prominent intra- and inter-tubular precipitates in both γ-PGA and γ-PGA/TCP groups. The XRD patterns of the deposition structures in all groups were similar to those of sound dentin, and the contact angle of water decreased after γ-PGA/TCP treatment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfatos de Calcio / Ácido Glutámico Límite: Animals Idioma: En Revista: Dent Mater J Año: 2021 Tipo del documento: Article Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfatos de Calcio / Ácido Glutámico Límite: Animals Idioma: En Revista: Dent Mater J Año: 2021 Tipo del documento: Article Pais de publicación: Japón