Finding new cancer epigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq and machine learning.
Comput Struct Biotechnol J
; 18: 1891-1903, 2020.
Article
en En
| MEDLINE
| ID: mdl-32774784
ATAC-seq, Assay for Transposase-Accessible Chromatin-sequencing and high-throughput sequencing; AUC, Area Under Curve; Biomarkers; CTC, circulating tumor cell; Cell-free DNA; ESCA, esophageal cancer; Esophageal cancer; NGS, next generation sequencing; NIPT, noninvasive prenatal testing; Next generation sequencing; PCA, principal component analysis; SALP-seq; SALP-seq, Single strand Adaptor Library Preparation-sequencing; SNP, single nucleotide polymorphism; SNV, single nucleotide variant; TCGA, The Cancer Genome Atlas; TF, transcription factor; TFBS, TF binding site; TSS, transcription start site; Ti, transitions; Tv, transversion; cfDNA, cell-free DNA; cfMeDIP-seq, cell-free methylated DNA immunoprecipitation and high-throughput sequencing; ctDNA, cell-free tumor DNA; mRNA, messenger RNA; miRNA, microRNA
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Idioma:
En
Revista:
Comput Struct Biotechnol J
Año:
2020
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Países Bajos