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Correlations between indices of dynamic components of ambulatory blood pressure and renal damage in elderly Chinese male with essential hypertension.
Leng, Wen-Xiu; Zhang, Meng; Cui, Hua; Zeng, Long-Huan; Hu, Yi-Xin.
Afiliación
  • Leng WX; Geriatric Cardiology Department of the Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital.
  • Zhang M; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College.
  • Cui H; Geriatric Cardiology Department of the Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital.
  • Zeng LH; Geriatric Cardiology Department of the Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital.
  • Hu YX; Clinical Department of Geriatrics of the Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China.
Blood Press Monit ; 25(6): 303-309, 2020 Dec.
Article en En | MEDLINE | ID: mdl-32769403
OBJECTIVE: Twenty-four-hour ambulatory blood pressure monitoring (ABPM) is an accurate method to document changes in blood pressure (BP) and is more predictive than office and home BP monitoring for cardiovascular outcomes in elderly people. We aimed to determine the relationship between ABPM indices and renal damage in elderly Chinese male patients with essential hypertension. METHODS: We investigated 998 Chinese men (mean age of 78.44 ± 12.02 years) with essential hypertension. Renal function, laboratory testing, and ABPM, including ABP, BP variability, and BP circadian rhythms were investigated. Data were shown according to BP controlling status. The relationships between ABPM indices and renal damage [expressed by urine protein, urine albumin/creatinine ratio (uACR), estimated glomerular filtration rate (eGFR), blood urea nitrogen (BUN)] were assessed using multiple regression analysis. RESULTS: After adjustments for age, common cardiovascular risk factors, and medications, uACR level was positively associated with 24-h mean systolic blood pressure (SBP), 24-h mean pulse pressure (PP), and 24-h SBP percent time of elevation. eGFR level was negatively associated with the 24-h mean SBP and 24-h mean PP. BUN level was positively correlated with the 24-h mean SBP, 24-h mean PP, and 24-h SBP percent time of elevation, whereas the BUN level was negatively associated with the 24-h DBP SD. CONCLUSION: The ABPM indices associated with renal damage may be regarded as an early predictive marker for renal function impairment in Chinese elderly male patients with hypertension.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Monitoreo Ambulatorio de la Presión Arterial Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Humans / Male Idioma: En Revista: Blood Press Monit Asunto de la revista: ANGIOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Monitoreo Ambulatorio de la Presión Arterial Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Humans / Male Idioma: En Revista: Blood Press Monit Asunto de la revista: ANGIOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido